Search
for

    Did you mean Keratin 6?
    Glossary Keratin 6

    protein in skin, hair, and nails providing structural support

    Keratin 6 (K6) is a type of protein found in the epithelial cells of the skin, hair, and nails. It plays a crucial role in the structural integrity and resilience of these tissues. Mutations in the KRT6 gene, which encodes Keratin 6, can lead to disorders such as pachyonychia congenita, characterized by thickened nails and other skin abnormalities.

    Related Terms

    Sort by

    Research 30 of 1000+

    1. Abstract 5022: Keratin15 (Krt15) + are radio resistant and tumor-initiating cells in the mouse small intestine Cancer Research · 2017
    2. Prolactin—a novel neuroendocrine regulator of human keratin expression<i>in situ</i> The FASEB Journal · 2010 · 64 citations
    3. The human keratins: biology and pathology Histochemistry and Cell Biology · 2008 · 1398 citations
    4. Efficient In Vivo Targeting of Epidermal Stem Cells by Early Gestational Intraamniotic Injection of Lentiviral Vector Driven by the Keratin 5 Promoter Molecular Therapy · 2007 · 52 citations
    5. Assembly of Hair Keratins in Transfected Epithelial Cells Biochemical and Biophysical Research Communications · 1996 · 5 citations
    6. Faculty Opinions recommendation of The keratins of the human beard hair medulla: the riddle in the middle. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2010
    7. Conditional Gene Expression in the Epidermis of Transgenic Mice Using the Tetracycline-Regulated Transactivators tTA and rTA Linked to the Keratin 5 Promoter Journal of Investigative Dermatology · 2000 · 215 citations
    8. Differential Evolution of the Epidermal Keratin Cytoskeleton in Terrestrial and Aquatic Mammals Molecular Biology and Evolution · 2018 · 68 citations
    9. Vibrissa hair bulge houses two populations of skin epithelial stem cells distinct by their keratin profile ˜The œFASEB journal · 2007 · 45 citations
    10. Biochemical and immunohistochemical analyses of keratin expression in basal cell carcinoma Journal of Dermatological Science · 1998 · 37 citations
    11. Development, Structure, and Keratin Expression in <i>C57BL/6J</i> Mouse Eccrine Glands Veterinary pathology · 2011 · 29 citations
    12. KERATINS AND SKIN DISORDERS Cell biology international · 1996 · 28 citations
    13. Keratin expression by corneal and limbal stem cells during development 2020 · 25 citations
    14. Genetic disorders of keratin: are scarring alopecias a sub-set? Journal of Dermatological Science · 1994 · 14 citations
    15. Structural heterogeneity of cellular K5/K14 filaments as revealed by cryo-electron microscopy Zurich Open Repository and Archive (University of Zurich) · 2021
    16. Keratin pattern in hyperkeratotic and ulcerated gastric pars oesophagea in pigs 1997 · 13 citations
    17. Expression patterns of hair and epithelial keratins and transcription factors HOXC13, LEF1, and β‐catenin in a malignant pilomatricoma: a histological and immunohistochemical study Journal of Cutaneous Pathology · 2005 · 27 citations
    18. Study on the distribution of hair keratin in normal hair follicles by immunohistochemical staining Acta Academiae Medicine Militaris Tertiae · 2000
    19. Expression of hair keratins in the adult nail unit: an immunohistochemical analysis of the onychogenesis in the proximal nail fold, matrix and nail bed British Journal of Dermatology · 2004 · 110 citations
    20. Epidermolysis bullosa simplex: a paradigm for disorders of tissue fragility 2009 · 189 citations
    21. Defining the complex epithelia that comprise the canine claw with molecular markers of differentiation Veterinary Dermatology · 2009 · 6 citations
    22. Nestin is a marker of unipotent embryonic and adult progenitors differentiating into an epithelial cell lineage of the hair follicles Scientific reports · 2022 · 1 citations
    23. Nestin as a marker of unipotent epithelial progenitor cells differentiate into outer root sheath keratinocytes in embryonic and adult hair follicles Research Square (Research Square) · 2022
    24. Lineage Tracing of Hair Follicle Stem Cells in Epidermal Whole Mounts Methods in molecular biology · 2013 · 11 citations
    25. Transdifferentiation of corneal epithelium: evidence for a linkage between the segregation of epidermal stem cells and the induction of hair follicles during embryogenesis. The International Journal of Developmental Biology · 2004 · 55 citations
    26. Type II Keratins Are Phosphorylated on a Unique Motif during Stress and Mitosis in Tissues and Cultured Cells Molecular Biology of the Cell · 2002 · 80 citations
    27. Directed Expression of a Chimeric Type II Keratin Partially Rescues Keratin 5-null Mice Journal of Biological Chemistry · 2014 · 15 citations
    28. The Type I Keratin 19 Possesses Distinct and Context-dependent Assembly Properties Journal of Biological Chemistry · 1998 · 46 citations
    29. Keratins as an Inflammation Trigger Point in Epidermolysis Bullosa Simplex International Journal of Molecular Sciences · 2021 · 40 citations
    30. cDNA Cloning, Expression, and Assembly Characteristics of Mouse Keratin 16 Journal of Biological Chemistry · 1998 · 32 citations