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In this case report, a 40-year-old woman with systemic lupus erythematosus developed Type B Insulin Resistance Syndrome, characterized by severe hyperglycemia despite high insulin doses, requiring immunosuppressive therapy to manage refractory symptoms.

This study found that women with PCOS exhibited higher levels of depression, tension induction, and impaired stress coping strategies compared to healthy controls, with these psychological issues correlating with hyperandrogenism but not with central obesity or insulin resistance.

This review found that insulin resistance is a significant independent factor in the development of various inflammatory skin diseases, often linked with obesity and metabolic disorders, and suggests measuring HOMA-IR in affected patients.

This study found that Pik3r1 Y657* mice, which model human SHORT syndrome, show increased energy expenditure despite insulin resistance, but this is not due to changes in locomotion, thermoregulation, or Ucp1-dependent thermogenesis, suggesting a different metabolic mechanism may protect against lipotoxicity.

This study found that a hydrogel formulation containing insulin, chitosan, and hydroxypropyl methyl cellulose improved wound healing in diabetic mice, promoting faster wound closure and organized tissue formation, with in vitro tests showing no cytotoxicity and enhanced cell migration.

In this study, researchers in Baghdad observed that women with PCOS who tested positive for CagA-IgG, a marker for H. pylori infection, showed significantly elevated insulin resistance and fasting blood sugar levels, regardless of metformin treatment, compared to controls.

This study reported a significant association between insulin resistance and acne vulgaris, with a higher prevalence of insulin resistance observed among acne patients compared to healthy controls.

This study found that in women with PCOS, insulin resistance is closely associated with hyperandrogenism, indicating it may independently predict increased androgen levels.

In this study, patients with androgenic alopecia were found to have higher levels of insulin, glucose, and HOMA-IR compared to healthy individuals, suggesting distinct metabolic profiles that may contribute to the condition's development.

This study observed that IGF-1R expression significantly decreased in basal keratinocytes of sacrococcygeal pilonidal sinus tissues, suggesting a potential role in its etiology, although further data are needed to evaluate its treatment implications.

This study identified 18 significant metabolites and two enriched metabolic pathways, necroptosis and ABC transporters, in serum samples of acne patients with and without insulin resistance, potentially aiding in the clinical diagnosis and drug development for these patients.

This study found that obese and overweight children have higher prevalence of certain skin disorders like keratosis pilaris and acanthosis nigricans, with these conditions being linked to insulin resistance and more likely in children with darker skin tones.

This study investigated the association between hair loss and medications affecting the GH/IGF-1 pathway, using the FDA Adverse Event Reporting System to analyze reporting odds ratios of alopecia.

In this study, CoQ10 and selenium nanoparticles showed potential to alleviate hyperlipidemia and simvastatin-induced side effects in rats, but a triple combination with simvastatin caused intense liver and muscle damage.

This study found that female adolescents with pilonidal sinus disease had significantly higher insulin levels and HOMA-IR scores, suggesting hyperinsulinemia may be a risk factor for the condition.

In this study, a high inositol diet, with or without supplements, significantly improved androgen levels, insulin sensitivity, and certain metabolic indicators in women with PCOS over three months.

This review discusses the clinical significance, mechanisms, and treatment options of insulin resistance, emphasizing its impact on endocrine diseases and the need for further research into inflammatory cytokines.

This study reviews polycystic ovary syndrome and vitamin D, reporting no new results, and notes the involvement of vitamin D receptors and insulin in ovarian function.

This study found that one-third of females with acne and PCOS also showed insulin resistance, suggesting that women with these conditions should be evaluated for impaired glucose tolerance.

This study found that individuals with homozygous loss-of-function mutations in PLAAT3 experience a novel type of partial lipodystrophy linked to defects in white adipose tissue differentiation and function.

This study observed that patients with acne vulgaris had significantly lower serum vaspin levels and higher insulin resistance, suggesting a potential role of vaspin in the disease's pathogenesis.

This study found that duodenal mucosal resurfacing did not significantly improve insulin sensitivity or reproductive function in women with PCOS and insulin resistance compared to a sham procedure.

This study suggests that high nesfatin-1 levels and insulin resistance are linked to an increased risk and severity of acne vulgaris.

This article reviews treatment approaches for polycystic ovary syndrome, highlighting lifestyle changes, medications like metformin for insulin resistance, and fertility therapies, acknowledging the complexities and contraindications involved.

This case report suggests that a supplement containing biotin, beta carotene, vitamin C, zinc, and copper may improve insulin resistance markers and hair loss in a patient with non-classic 11-hydroxylase deficiency.

This study found that in male mouse pancreatic islet β cells, testosterone enhances glucose-stimulated insulin secretion by being locally converted into dihydrotestosterone and estradiol.

In this case study, the researchers reported that treating a woman with type B insulin resistance using rituximab, dexamethasone, and cyclophosphamide greatly reduced her insulin needs, but her hyperandrogenic state persisted, suggesting ovarian hyperthecosis.

This study found that vitamin D supplementation increased the cumulative ovulation rate in vitamin D deficient women with polycystic ovary syndrome compared to those with normal vitamin D levels and a control group.

This case report describes a 28-year-old woman with facial, abdominal, and thigh hirsutism who showed little improvement after 5 months of Metformin and spironolactone treatment.

This review examines the development, pathogenesis, and effects of insulin resistance, highlighting its connections to numerous health conditions, without presenting new research findings.