TLDR Lower vaspin levels are linked to more severe acne and higher insulin resistance.
This study assessed the serum level of vaspin in 52 patients with acne vulgaris (AV) and its relation to insulin resistance, compared to 32 control subjects. The findings indicated that patients with AV had significantly lower levels of vaspin and higher levels of fasting blood glucose, fasting insulin, and HOMA-IR compared to the control group. A significant positive correlation was observed between HOMA-IR and the severity of AV, while vaspin showed a significant negative correlation with HOMA-IR in the AV group. These results suggested that serum vaspin played a role in the pathogenesis of acne vulgaris and was inversely related to insulin resistance in these patients.
2 citations
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January 2019 in “Egyptian Journal of Dermatology and Venereology” Insulin might be involved in causing hair loss and acne.
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July 2018 in “The Egyptian Journal of Hospital Medicine” The conclusion is that antibiotics are not the best acne treatment and early treatment is important to prevent scarring, especially for those with a family history of acne.
99 citations
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December 2010 in “Journal of The European Academy of Dermatology and Venereology” The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.
November 2001 in “Hair transplant forum international” Early hair loss might indicate insulin resistance.
6 citations
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December 2022 in “International Journal of Molecular Sciences” Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.
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February 2023 in “BMC women's health” Birth control pills change the activity of certain inflammation and blood clotting genes in women with PCOS.
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November 2020 in “International journal of molecular sciences” Adipokines affect skin health and could be targeted for treating skin diseases.
132 citations
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January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
38 citations
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January 2011 in “Endocrine Journal” Weight loss and metformin don't significantly change vaspin levels in women with PCOS.
