In Vitro and In Vivo Evaluation of Chitosan/HPMC/Insulin Hydrogel for Wound Healing Applications

    February 2024 in “ Bioengineering ”
    Flávia Cristina Zanchetta, Pieter De Wever, Joseane Morari … Pedro Fardim
    Studysummary This study found that a hydrogel formulation containing insulin, chitosan, and hydroxypropyl methyl cellulose improved wound healing in diabetic mice, promoting faster wound closure and organized tissue formation, with in vitro tests showing no cytotoxicity and enhanced cell migration.
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    Research cited in this study 2

    1. Living Microecological Hydrogels for Wound Healing Science Advances · 2023
    2. Skin Manifestations of Insulin Resistance: From a Biochemical Stance to a Clinical Diagnosis and Management Dermatology and Therapy · 2016