A Rare Case of Type B Insulin Resistance Syndrome

October 2024 in “ Journal of the Endocrine Society ”

Sanna Fatima, Amber Champion, Samuel Ward, Qurrat-ul-ain Aziz, Kenneth Izuora

hair loss insulin resistance autoantibody insulin receptor methylprednisolone cyclophosphamide rituximab hydroxychloroquine IV immunoglobulin steroid immunosuppressive therapy Plaquenil IVIG

Studysummary In this case report, a 40-year-old woman with systemic lupus erythematosus developed Type B Insulin Resistance Syndrome, characterized by severe hyperglycemia despite high insulin doses, requiring immunosuppressive therapy to manage refractory symptoms.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer ·

View this study on academic.oup.com →

Discuss this study in the Community →

Similar Research

5 / 1000+ results

research Syndromes of Severe Insulin Resistance (SSIRs)

November 2004

This review discusses various syndromes of severe insulin resistance, their biochemical and clinical features, and potential therapeutic options, but it reports no new clinical results.

research SAT-240 Type B Insulin Resistance Resulting in Hyperthecosis in a Postmenopausal Woman

April 2019 in “Journal of the Endocrine Society”

In this case study, the researchers reported that treating a woman with type B insulin resistance using rituximab, dexamethasone, and cyclophosphamide greatly reduced her insulin needs, but her hyperandrogenic state persisted, suggesting ovarian hyperthecosis.

Type A Insulin Resistance Syndrome Due to a Novel Heterozygous c.3486_3503del (p. Arg1163_Ala1168del) INSR Gene Mutation in an Adolescent Girl and Her Mother

research Type A insulin resistance syndrome due to a novel heterozygous c.3486_3503del (p. Arg1163_Ala1168del) INSR gene mutation in an adolescent girl and her mother

January 2024 in “Archives of Endocrinology and Metabolism”

In this case report, a novel heterozygous mutation in the insulin receptor gene was identified in an adolescent girl with type A insulin resistance syndrome, characterized by excessive hair growth and skin changes, and her mother.

research SAT-293 Novel Presentation Of A Heterozygous INSR Mutation And Markedly Elevated Testosterone Levels In A Pediatric Patient, A Case Report.

April 2019 in “Journal of the Endocrine Society”

In this case report, significantly elevated testosterone levels were documented in a young female with Type A Insulin Resistance Syndrome, marking a clinical finding beyond what is typically associated with the disorder's known mutations.

Acanthosis Nigricans During HAIR-AN Syndrome: The Tree That Hides the Forest

research Acanthosis Nigricans during an HAIR-AN syndrome: "The Tree That Hides the Forest"

January 2017 in “Journal of clinical & experimental dermatology research”

This report describes a case of HAIR-AN syndrome in a young woman, characterized by acanthosis nigricans, insulin resistance, and polycystic ovaries, highlighting its rarity and multisystem nature.