Alopecia Areata: Autoimmune Nature, Genetic Associations, and Treatments

    August 2005 in “ Springer eBooks
    Pia Freyschmidt‐Paul, Kevin J. McElwee, Rolf Hoffmann
    TLDR Alopecia areata is an autoimmune disease with genetic links, treatable with certain medications, and can affect mental health.
    The document reviewed various studies and clinical observations related to alopecia areata, highlighting its autoimmune nature and genetic associations. It discussed treatments such as intralesional triamcinolone acetonide, topical minoxidil, and PUVA therapy, and noted the involvement of HLA antigens and cytokines in the disease's pathogenesis. The document also mentioned the occurrence of alopecia areata in families and its association with other autoimmune conditions, such as thyroid disease and Down syndrome. Additionally, it referenced the psychological impact of alopecia areata and the role of T lymphocytes in mediating the condition.
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