Insulin Resistance Syndrome: The Sensitive IRS

January 2018

Eleni Pellazgu

TLDR Insulin resistance is linked to many health problems and is influenced by diet, genetics, and other factors.

The document from 2018, "Insulin Resistance Syndrome- the Sensitive IRS," by Pellazgu, E., reviewed the pathophysiology of insulin resistance and its association with various metabolic disorders such as obesity, prediabetes, type 2 Diabetes Mellitus, impaired glucose tolerance, dyslipidemia, polycystic ovary syndrome, and hypercoagulability. The paper also highlighted the syndrome's strong links with conditions like obstructive sleep apnea, hypoventilation syndrome, pancreatitis, nonalcoholic fatty liver disease, multiple cancers, stroke, coronary heart disease, and hypertension. The author discussed the intrinsic and extrinsic factors contributing to the development of insulin resistance and its lasting effects on metabolism, behavior, and physical appearance. The paper aimed to raise awareness of the role of diet, metabolic factors, genetics, and the microbiome in insulin resistance.

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