Prevalence and Predictors of Impaired Glucose Tolerance and Type 2 Diabetes Mellitus in Patients with Polycystic Ovary Syndrome
TLDR Many women with polycystic ovary syndrome have normal blood sugar, but some may have higher blood sugar levels or diabetes, especially if they are older, overweight, and have certain hormone levels.
The study involved 80 women with newly diagnosed polycystic ovary syndrome (PCOS) and aimed to estimate the prevalence of impaired glucose tolerance (IGT) and diabetes mellitus type 2 (DMT2), and identify predictors for glucose abnormalities. Results showed that 63% of participants had normal glucose tolerance, 23% had IGT, and 9% had DMT2. Age, body mass index (BMI), sex hormone bounding globulin (SHBG), and testosterone levels were identified as major independent predictors for abnormal glucose metabolism. The study concluded that the prevalence of IGT and DMT2 among PCOS women in their country is lower than in Western countries. However, older, obese women with low SHBG levels need close monitoring due to their higher risk for developing IGT and DMT2.
