15 citations
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March 2018 in “Journal of The American Academy of Dermatology” This study found that platelet-rich plasma combined with other hair restoration therapies significantly increased hair density in patients with androgenetic alopecia, though it did not statistically affect hair shaft diameter.
11 citations
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August 2021 in “Stem Cell Research & Therapy” This study reports that a single transplantation of autologous stromal vascular fraction significantly increased hair density and keratin score in androgenic alopecia patients within six months.
10 citations
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August 2018 in “Dermatologic Surgery” This study found that 1,550-nm Er:Glass fractional laser treatment increased hair density and shaft diameter in patients with androgenetic alopecia, but did not up-regulate Wnt10A and IGF-1 mRNA expression.
9 citations
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November 2021 in “PubMed” This study found that FDA-approved low-level light/laser therapy devices significantly increased hair density in individuals with pattern hair loss compared to sham devices.
5 citations
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January 2021 in “Journal of Cosmetic Dermatology” This study found that adding platelet-rich plasma with microneedling to conventional medical treatment significantly increased hair density and diameter in androgenetic alopecia patients compared to medical treatment alone.
5 citations
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January 2011 This study found that Gyungohkgo-gamibang extract and minoxidil both significantly stimulated hair growth and increased hair density and thickness in C57BL/6 mice compared to a vehicle treatment.
3 citations
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January 2018 in “Cirugía Plástica Ibero-Latinoamericana” This study found that intradermal PRP injections may reduce hair loss and increase hair density in patients with non-scarring alopecia, with differences in the response time between men and women.
1 citations
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June 2022 in “Photobiomodulation, photomedicine, and laser surgery” In this study, photobiomodulation notably increased hair density in men with androgenetic alopecia after 5 weeks, though no further gains were observed with additional sessions.
1 citations
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January 2011 in “Journal of S C C J” In this study, adenosine lotion significantly increased the proportion of thick hair among women with hair loss compared to placebo, showing potential as a safe and effective treatment without observed side effects.
September 2024 in “Journal of Dental Specialities” This study found that platelet-rich plasma combined with micro-needling significantly increased hair density and thickness in patients with androgenetic alopecia, with mild side effects reported, though further high-quality trials are needed to validate these results and standardize treatments.
This randomized control trial reported that mesenchymal stem cell-derived exosomes significantly increased hair density and thickness in patients with androgenic alopecia, with a mean increase of 35 hairs/cm² over 12 weeks compared to the placebo group, which showed minimal hair density changes.
December 2023 in “Siriraj Medical Journal” This study found that 5% azelaic acid solution and 2% minoxidil solution both significantly increased hair density and shaft diameter in women with FPHL, with no significant differences between them.
January 2023 in “Turk Dermatoloji Dergisi” In a single case study, researchers reported increased hair density using a trypsin-isolated cell suspension containing CD34 and CD200 positive cells for treating grade III androgenetic alopecia.
This case report observed that a 44-year-old male patient with androgenetic alopecia experienced increased hair density and patient satisfaction after treatment with microneedling, growth factors, and minoxidil.
September 2017 in “Journal of Clinical Dermatology” This study found that applying a growth factor cocktail including FGF9 with microneedling significantly increased hair density and diameter in patients with androgenetic alopecia, with similar results regardless of microneedle depths between 0.5 mm and 0.8 mm.
February 2016 in “Aktuelle Dermatologie” This study found that 6 months of Low-Level-Laser Therapy significantly increased overall hair density, particularly Vellus hair density, in women with hormonal, age-related hair loss.
June 2022 in “Journal of Cosmetic Dermatology” This study found that combining botulinum toxin A injections with finasteride and minoxidil increased hair density in patients with androgenic alopecia more effectively than finasteride and minoxidil alone.
April 2022 in “Journal of advances in medicine and medical research” This study found that applying topical minoxidil 5% twice daily for 24 weeks increased hair density and width in men with androgenetic alopecia, although the change in clinical hair grading was not statistically significant.
May 2021 in “IP Indian journal of clinical and experimental dermatology” This study found that combining topical 5% minoxidil with autologous PRP therapy significantly increased hair density in men with androgenetic alopecia compared to minoxidil alone, without major side effects.
August 2020 in “Actas Dermo-Sifiliográficas” This study found that platelet rich plasma injections led to a 19.17% increase in hair density in males with androgenetic alopecia, although response did not correlate with age or duration of the condition.
June 2020 in “Journal of Evolution of medical and Dental Sciences” This study found that platelet-rich plasma treatment effectively decreased hair fall and increased hair growth in male patients with androgenetic alopecia.
18 citations
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January 2018 in “International journal of medical sciences” This study found that non-thermal plasma treatment increased epidermal thickness and dermal collagen density in mouse skin tissue without causing damage, potentially promoting growth factors and tissue remodeling.
3 citations
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March 2013 in “PubMed” This study found that applying 10% platelet-rich plasma significantly increased hair follicle density and reduced the time for hair formation in a mouse model compared to no PRP treatment.
This study suggests that autologous platelet-rich plasma injections may increase terminal hair density in women with androgenetic alopecia, without significantly affecting hair thickness.
72 citations
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April 2008 in “The Journal of urology/The journal of urology” This study found that 1-year use of 5alpha-reductase inhibitors, dutasteride or finasteride, significantly lowered dihydrotestosterone levels without adversely affecting bone density, lipids, or hemoglobin in normal men.
41 citations
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January 2020 in “BioMed Research International” This study found that micrografts containing human hair follicle mesenchymal stem cells significantly increased hair count and density compared to placebo over 58 weeks in patients experiencing hair loss.
29 citations
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January 2018 in “International Journal of Trichology” This meta-analysis reported that platelet-rich plasma injections for androgenetic alopecia may increase hair number and thickness locally, but further studies are needed to establish their overall effectiveness.
28 citations
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December 2002 in “Der Hautarzt” TrichoScan accurately measures hair growth and loss, showing increased hair counts and thickness with treatment.
27 citations
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January 2015 in “International Journal of Trichology” This study found that a marine-extract dietary supplement significantly reduced hair shedding and increased hair diameter in premenopausal women with subclinical hair thinning or hair loss after 6 months of use.
19 citations
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July 2015 in “Journal of inherited metabolic disease” This study observed that while betaine supplementation decreases total homocysteine and increases methionine levels in a mouse model of CBS deficiency, it is not as effective as methionine restriction in reversing associated phenotypes.