The Effect of Gyungokgo-Gamibang Extract on Hair Growth and Protein Expression in Mice

The study investigated the effects of Gyungokgo-gamibang extract (YNS-10) on hair growth and protein expression in C57BL/6 mice with alopecia. Mice were treated with either YNS-10, 5% minoxidil, or a vehicle for 3 weeks. Results showed that both YNS-10 and minoxidil significantly stimulated hair growth, increasing hair density by approximately 210% and 200%, respectively, and hair thickness by about 210% and 220%, respectively, compared to the vehicle. Additionally, the expression of growth factors IGF-1 and VEGF was significantly up-regulated in the YNS-10 and minoxidil groups. The findings suggested that YNS-10 could be a potent ingredient for hair growth treatments.