TLDR Gyungokgo-gamibang extract significantly promotes hair growth and increases hair thickness.
The study investigated the effects of Gyungokgo-gamibang extract (YNS-10) on hair growth and protein expression in C57BL/6 mice with alopecia. Mice were treated with either YNS-10, 5% minoxidil, or a vehicle for 3 weeks. Results showed that both YNS-10 and minoxidil significantly stimulated hair growth, increasing hair density by approximately 210% and 200%, respectively, and hair thickness by about 210% and 220%, respectively, compared to the vehicle. Additionally, the expression of growth factors IGF-1 and VEGF was significantly up-regulated in the YNS-10 and minoxidil groups. The findings suggested that YNS-10 could be a potent ingredient for hair growth treatments.
38 citations
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June 2005 in “Contact Dermatitis” Patient had scalp allergy from minoxidil; test helped identify cause and suggest alternative treatments.
118 citations
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April 1998 in “Dermatologic Clinics” Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.
19 citations
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October 1989 in “PubMed” This study from 1989 investigated the sulfation of minoxidil in different skin cells, including hair follicles, keratinocytes, and fibroblasts, to understand its role in hair growth stimulation. The researchers found that sulfation of minoxidil occurred significantly in hair follicles and proliferative keratinocytes, while it was very low in differentiating keratinocytes and fibroblasts. The strong sulfation activity in hair follicle cells suggested a potential link to the hair growth-stimulating effects of minoxidil.
December 2015 in “OPAL (Open@LaTrobe) (La Trobe University)”
81 citations
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July 2011 in “Lasers in Medical Science” The Lexington LaserComb helped regrow hair in mice with a condition similar to human hair loss.
4 citations
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January 2010 in “Laboratory Animal Research” Sodium silicate helped mouse hair grow similarly to a known hair growth treatment.
5 citations
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July 2003 in “Drug Development Research” Fluridil promotes hair growth safely and effectively for androgenetic alopecia.