June 2020 in “Aesthetic Surgery Journal” This study found that PRP with high estrogen levels increased hair density more effectively and earlier than autologous PRP in male patients with androgenic alopecia.
January 2020 in “Journal of Clinical Dermatology” This study found that oral dutasteride significantly increased hair density but not thickness in women with female-pattern hair loss, and identified a mechanism involving β-catenin activation.
December 2018 in “Вестник Российской Военно-медицинской академии” This study reported that platelet-rich plasma therapy significantly increased hair density and diameter in men with androgenetic alopecia by inducing morphological changes in hair follicles.
July 2016 in “Chinese Journal of Dermatology” This study found that low-level laser therapy increased hair density in men with androgenetic alopecia, with even greater improvements seen when combined with finasteride.
10 citations
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October 2021 in “Animal nutrition” This study found that dietary pyridoxine increased hair follicle density in Rex rabbits by activating PI3K/Akt, Wnt, and Notch signaling pathways, which may promote hair growth and delay telogen onset.
269 citations
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August 2002 in “Journal of The American Academy of Dermatology” This study found that 5% topical minoxidil significantly increased hair regrowth and improved psychosocial perceptions of hair loss in men with androgenetic alopecia compared to 2% topical minoxidil and placebo over 48 weeks.
90 citations
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October 1983 in “British Journal of Dermatology” This study found that individuals with androgenic alopecia have an increased number of thin hairs (less than 40 microns in diameter) per cm², which may affect their clinical appearance.
21 citations
,
January 2012 in “Annals of Dermatology” This study reported that Ell-Cranell® alpha 0.025% solution significantly increased hair counts and diameter in Korean women with female pattern hair loss over an 8-month period, showing both efficacy and safety.
12 citations
,
March 2019 in “Journal of Cosmetic Dermatology” This study found that platelet-rich plasma may effectively increase hair follicle numbers in men with androgenetic alopecia, but changes in hair thickness plateaued after the second injection.
4 citations
,
June 2020 in “Cosmetics” This study reports that Broussonetia papyrifera extract significantly increased hair count over 12 weeks in a small clinical trial and promoted dermal papilla cell proliferation in vitro by regulating WNT-β-catenin and STAT6 pathways.
3 citations
,
January 1994 in “Journal of Society of Cosmetic Chemists of Japan” This study found that a hair tonic increased hair growth and reduced resting hair ratios in men with alopecia.
2 citations
,
September 2021 in “Universal Journal of Pharmaceutical Research” This study found significant associations between polycystic ovary syndrome and increased serum levels of reproductive hormones, as well as connections to infertility, hirsutism, and metabolic syndrome in Yemeni women.
1 citations
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December 2018 in “LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)” This study found that combining electrotherapy with aromatherapy led to increased hair shaft thickness in men with androgenetic alopecia, although no changes in the scalp were observed.
January 2026 in “Journal of the American Academy of Dermatology” 5-alpha reductase inhibitors do not increase osteoporosis risk in women with certain hair loss conditions.
March 2025 in “Journal of Dermatological Treatment” This study explored whether using topical minoxidil can temporarily increase hair shedding, but results are not reported.
February 2024 in “Clinical, Cosmetic and Investigational Dermatology” This study reports a solid causal relationship between increased serum levels of ApoB, LDL, and VLDL and an elevated risk of androgenic alopecia.
January 2024 in “Journal of Cosmetic Dermatology” This systematic review found that platelet-rich plasma may increase hair density and count in male androgenetic alopecia, though limitations in study quality and consistency suggest further research is needed.
This study found that platelet-rich plasma injections significantly increased hair count and improved hair loss in patients with androgenic alopecia, with high patient satisfaction and no notable adverse effects.
January 2022 in “Cosmoderma” This study found that combining oral minoxidil with dutasteride increased hair thickness, density, and new growth in male pattern baldness patients with minimal side effects.
January 2022 in “Experimental Dermatology” Minoxidil solution and foam both increase hair growth, but the solution works better than the foam.
July 2026 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study highlights that topical melatonin formulations have the potential to increase hair density, prolong the hair growth phase, and reduce shedding in adults with alopecia, while generally being safe, though further large-scale randomized trials are needed to confirm its clinical efficacy.
This review of SVF treatment for androgenetic alopecia found a significant increase in hair density across studies with no serious adverse events, but calls for standardized protocols and further research.
31 citations
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August 2001 in “PubMed” This study found that the TrichoScan method detected significant increases in hair counts and cumulative hair thickness in men after finasteride treatment, suggesting its potential for monitoring hair treatment responses.
This study found that topical application of Sinsun-yukza-hwan extract significantly increased hair density and thickness in a mouse alopecia model and enhanced expression of growth-related genes.
47 citations
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August 2011 in “Journal of The European Academy of Dermatology and Venereology” This study found that treatment with a 1550 nm fractional erbium–glass laser increased hair density and thickness in women with female pattern hair loss, suggesting it may be an effective and safe option.
40 citations
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March 2018 in “Aesthetic Surgery Journal” This study found that a single injection of platelet-rich stroma significantly increased hair density in men with androgenetic alopecia within 6 to 12 weeks, with no reported side effects.
30 citations
,
October 2013 in “BMC dermatology” In this animal study, topical VEGF gel increased hair growth and thickness in Mesocricetus auratus, although it was not completely inert, highlighting the need for further toxicity confirmation.
29 citations
,
October 2020 in “eLife” This study using Mendelian randomization in UK Biobank data suggests that lifelong increased free testosterone may have mixed effects, including increased bone density and prostate cancer risk, warranting well-powered trials to address uncertainties.
26 citations
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May 2017 in “Lasers in Medical Science” This study found that combining ablative fractional CO₂ laser therapy with hair growth factors significantly increased hair density in men with androgenetic alopecia compared to using growth factors alone.
25 citations
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August 2016 in “Journal of Cosmetic Dermatology” This study found that a marine complex supplement significantly reduced hair shedding and increased hair growth in men with thinning hair over 180 days.