Does the Transient Hair Shedding Phase Exist After Minoxidil Treatment and Predict Treatment Efficacy? A Retrospective Study in Androgenetic Alopecia Patients

    March 2025 in “ Journal of Dermatological Treatment ”
    Lingbo Bi, Haili Kan, Jing Wang … Weixin Fan
    Studysummary This study explored whether using topical minoxidil can temporarily increase hair shedding, but results are not reported.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 26

    1. Assessing the Safety of Topical Minoxidil Through Disproportionality Analysis of FAERS Reports Expert Opinion on Drug Safety · 2025
    2. Low-Dose Oral Minoxidil in a Case of Short Anagen Syndrome Journal of Dermatological Treatment · 2025
    3. Male Androgenetic Alopecia Anais Brasileiros de Dermatologia · 2025
    4. Sublingual Minoxidil Increases Fiber Diameter in Male Androgenetic Alopecia: A Proxy for Reversal of Hair Follicle Miniaturization PubMed · 2025
    5. Comparing Adherence, Side Effects, And Satisfaction In Oral And Topical Minoxidil: A Cross-Sectional Study Journal of Drugs in Dermatology · 2025
    6. Combating Dread Shed: The Impact of Overlapping Topical and Oral Minoxidil on Temporary Hair Shedding During Oral Minoxidil Initiation JAAD International · 2024
    7. Minoxidil Sulfotransferase Enzymatical Activity in Plants: A Novel Paradigm in Increasing Minoxidil Response in Androgenetic Alopecia Journal of Cosmetic Dermatology · 2023
    8. Female Pattern Hair Loss: An Overview with Focus on the Genetics Genes · 2023
    9. Androgenetic Alopecia: Therapy Update Drugs · 2023
    10. Efficacy, Tolerability, and Superiority of Propylene Glycol-Free, North American Witch-Hazel-Based Solution of 5% Minoxidil Sulfate for the Treatment of Female Androgenetic Alopecia International Journal of Trichology · 2023
    11. Compliance to Topical Minoxidil and Reasons for Discontinuation Among Patients With Androgenetic Alopecia Dermatology and therapy · 2023
    12. Minoxidil: A Comprehensive Review Journal of Dermatological Treatment · 2021
    13. SULT1A1 (Minoxidil Sulfotransferase) Enzyme Booster Significantly Improves Response to Topical Minoxidil for Hair Regrowth Journal of Cosmetic Dermatology · 2021
    14. The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis Journal of The American Academy of Dermatology · 2017
    15. Sulfotransferase Activity in Plucked Hair Follicles Predicts Response to Topical Minoxidil in the Treatment of Female Androgenetic Alopecia Dermatologic Therapy · 2014
    16. Androgenetic Alopecia (Male Pattern Hair Loss) in the United States: What Treatments Should Primary Care Providers Recommend? Journal of the American Association of Nurse Practitioners · 2013
    17. Guidelines for Management of Androgenetic Alopecia Based on BASP Classification: The Asian Consensus Committee Guideline Journal of The European Academy of Dermatology and Venereology · 2012
    18. Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men Journal der Deutschen Dermatologischen Gesellschaft · 2011
    19. Minoxidil Activates β-Catenin Pathway in Human Dermal Papilla Cells: A Possible Explanation for Its Anagen Prolongation Effect Journal of Dermatological Science · 2011
    20. Molecular Basis of Androgenetic Alopecia: From Androgen to Paracrine Mediators Through Dermal Papilla Journal of Dermatological Science · 2010
    21. A New Classification of Pattern Hair Loss That Is Universal for Men and Women: Basic and Specific (BASP) Classification Journal of The American Academy of Dermatology · 2007
    22. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002
    23. Possible Mechanisms of Miniaturization During Androgenetic Alopecia or Pattern Hair Loss Journal of The American Academy of Dermatology · 2001
    24. Minoxidil Upregulates the Expression of Vascular Endothelial Growth Factor in Human Hair Dermal Papilla Cells British Journal of Dermatology · 1998
    25. Hair Anatomy for the Clinician Journal of The American Academy of Dermatology · 1991
    26. Safety and Efficacy of Topical Minoxidil in the Management of Androgenetic Alopecia Journal of The American Academy of Dermatology · 1987

    Related research 9

    1. Continued Year-On-Year Improvement in Hair Density With Systemic Minoxidil in Women With Female Pattern Hair Loss: A Case Series Journal of the American Academy of Dermatology · 2025
    2. Oral Finasteride (5 mg and 2 mg) Versus Topical Minoxidil 5% in Female Pattern Hair Loss Clinical Dermatology Review · 2025
    3. Hair Loss (Alopecia or Baldness) 2018
    4. Treatments of Hereditary Hair Loss (Alopecia) 2018
    5. Effects of Mixed Medicinal Herbal Extract on Hair Growth in Mice with Alopecia 2014
    6. Therapy Of Androgenetic Alopecia In Women With Minoxidil Solution Gynäkologische Endokrinologie · 2009
    7. Androgenetic Alopecia in Adolescents PubMed · 2003
    8. Effect of Minoxidil on Hair Growth in Androgenic Alopecia in Women PubMed · 2002
    9. Treatment of Hair Loss The New England Journal of Medicine · 1999