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    Oral Finasteride (5 mg and 2 mg) Versus Topical Minoxidil 5% in Female Pattern Hair Loss

    January 2025 in “ Clinical Dermatology Review ”
    Eman Hamed El Morsy, A Toto, Eman H. Hassan
    Studysummary In this study of female pattern hair loss, oral finasteride 5 mg and topical minoxidil 5% both significantly improved hair density and patient satisfaction over 6 months, outperforming finasteride 2 mg, which showed limited improvement beyond the third month. All treatments were deemed safe.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 30

    1. Pumpkin Seed Oil vs. Minoxidil 5% Topical Foam for the Treatment of Female Pattern Hair Loss: A Randomized Comparative Trial Journal of Cosmetic Dermatology · 2021
    2. Female Androgenetic Alopecia: An Update on Diagnosis and Management American Journal of Clinical Dermatology · 2019
    3. The Use of Trichoscopy to Assess the Efficacy of Topical Minoxidil 2% Solution in Patients with Female Pattern Hair Loss Zagazig university medical journal · 2019
    4. Minoxidil 1 mg Oral Versus Minoxidil 5% Topical Solution for the Treatment of Female-Pattern Hair Loss: A Randomized Clinical Trial Journal of The American Academy of Dermatology · 2019
    5. Androgens in Women: Hormone-Modulating Therapies for Androgen-Mediated Cutaneous Disorders Journal of The American Academy of Dermatology · 2018
    6. Efficacy of Topical Combination of 0.25% Finasteride and 3% Minoxidil Versus 3% Minoxidil Solution in Female Pattern Hair Loss: A Randomized, Double-Blind, Controlled Study American Journal of Clinical Dermatology · 2018
    7. Clinical Efficacy of Oral Administration of Finasteride at a Dose of 2.5 mg/Day in Women with Female Pattern Hair Loss Dermatologic Therapy · 2018
    8. Adverse Effects with Finasteride 5 mg/Day for Patterned Hair Loss in Premenopausal Women International Journal of Trichology · 2018
    9. Minoxidil Induction of VEGF Is Mediated by Inhibition of HIF-Prolyl Hydroxylase International Journal of Molecular Sciences · 2017
    10. Evaluation of Hair Density in Different Ethnicities in a Healthy American Population Using Quantitative Trichoscopic Analysis Skin Appendage Disorders · 2017
    11. Efficacy and Safety of a Topical Botanical in Female Androgenetic Alopecia: A Randomized, Single-Blinded, Vehicle-Controlled Study Skin appendage disorders · 2017
    12. Therapeutic Experience with Oral Finasteride for Androgenetic Alopecia in Female-to-Male Transgender Patients Clinical and Experimental Dermatology · 2017
    13. Low-Level Light and Minoxidil 5% Combination Versus Either Modality Alone in Management of Female Patterned Hair Loss: A Randomized Controlled Study Lasers in Surgery and Medicine · 2017
    14. Genetics and Other Factors in the Etiology of Female Pattern Hair Loss Experimental Dermatology · 2017
    15. Female Pattern Hair Loss: A Clinical and Pathophysiological Review Anais Brasileiros De Dermatologia · 2015
    16. Insulin-Like Growth Factor-1: Roles in Androgenetic Alopecia Experimental Dermatology · 2014
    17. Finasteride 5 mg/Day Treatment of Patterned Hair Loss in Normo-Androgenetic Postmenopausal Women International Journal of Trichology · 2013
    18. Efficacy of Finasteride 1.25 mg on Female Pattern Hair Loss: Pilot Study Annals of Dermatology · 2012
    19. A Randomized, Single-Blind Trial of 5% Minoxidil Foam Once Daily Versus 2% Minoxidil Solution Twice Daily in the Treatment of Androgenetic Alopecia in Women Journal of The American Academy of Dermatology · 2011
    20. 5 mg/Day Finasteride Treatment for Normoandrogenic Asian Women with Female Pattern Hair Loss Journal of The European Academy of Dermatology and Venereology · 2010
    21. Hair Loss in Women: Comprehensive Overview and Treatment Options Seminars in Cutaneous Medicine and Surgery · 2009
    22. Finasteride Treatment of Female Pattern Hair Loss Archives of Dermatology · 2006
    23. Prevalence of Male and Female Pattern Hair Loss in Maryborough Journal of Investigative Dermatology Symposium Proceedings · 2005
    24. The Reliability of Horizontally Sectioned Scalp Biopsies in the Diagnosis of Chronic Diffuse Telogen Hair Loss in Women Journal of The American Academy of Dermatology · 2004
    25. A Randomized, Placebo-Controlled Trial of 5% and 2% Topical Minoxidil Solutions in the Treatment of Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2004
    26. Finasteride Treatment of Patterned Hair Loss in Normoandrogenic Postmenopausal Women Dermatology · 2004
    27. Treatment of Hyperandrogenic Alopecia in Women Fertility and Sterility · 2003
    28. Hair Loss in Women with Hyperandrogenism: Four Cases Responding to Finasteride Journal of The American Academy of Dermatology · 2002
    29. Hair Diameter Diversity: A Clinical Sign Reflecting Follicle Miniaturization PubMed · 2001
    30. Lack of Efficacy of Finasteride in Postmenopausal Women with Androgenetic Alopecia Journal of The American Academy of Dermatology · 2000

    Related research 9

    1. Comparative Study of Topical Minoxidil (5%) Plus Finasteride (0.1%) Versus Platelet-Rich Plasma Plus Topical Minoxidil (5%) Plus Finasteride (0.1%) in Patients with Androgenic Alopecia Asian Journal of Pharmaceutical and Clinical Research · 2024
    2. Reply to: Comment on Bicalutamide Improves Minoxidil-Induced Hypertrichosis in Female Pattern Hair Loss: A Retrospective Review of 35 Patients Journal of The American Academy of Dermatology · 2022
    3. A Randomized, Double-Blind Controlled Study of the Efficacy and Safety of Topical Solution of 0.25% Finasteride Admixed with 3% Minoxidil vs. 3% Minoxidil Solution in the Treatment of Male Androgenetic Alopecia Journal of The European Academy of Dermatology and Venereology · 2018
    4. Efficacy of Non-Surgical Treatments for Androgenetic Alopecia: A Systematic Review and Network Meta-Analysis Journal of The European Academy of Dermatology and Venereology · 2018
    5. The Modern Treatment of Androgenetic Alopecia Vestnik dermatologii i venerologii · 2017
    6. Combined Treatment with Oral Finasteride and Topical Minoxidil in Male Androgenetic Alopecia: A Randomized and Comparative Study in Chinese Patients Dermatologic Therapy · 2015
    7. A New Topical Formulation of Minoxidil and Finasteride Improves Hair Growth in Men with Androgenetic Alopecia Journal of clinical & experimental dermatology research · 2015
    8. Diffuse Hypertrichosis During Treatment with 5% Topical Minoxidil British Journal of Dermatology · 1997
    9. Topical Minoxidil for Hair Regrowth Journal of The American Academy of Dermatology · 1984