Comparative Study of Topical Minoxidil (5%) Plus Finasteride (0.1%) Versus Platelet-Rich Plasma Plus Topical Minoxidil (5%) Plus Finasteride (0.1%) in Patients with Androgenic Alopecia

December 2024 in “ Asian Journal of Pharmaceutical and Clinical Research ”

DHARA D PATEL, SOM J LAKHANI, S. K. Shah, Krunal Tralsawala, ARTI BHABHOR

minoxidil finasteride platelet-rich plasma androgenic alopecia Rogaine Propecia PRP

TLDR Adding PRP to minoxidil and finasteride is more effective for hair loss.

This study compared the effectiveness of two treatments for androgenic alopecia in 50 male patients over a year. Group A received topical minoxidil (5%) and finasteride (0.1%), while Group B received the same topical treatment plus platelet-rich plasma (PRP) monthly for 6 months. Results showed that the PRP group had a significantly better response, with 65% showing good results compared to 26% in the non-PRP group. The study concludes that adding PRP to the conventional treatment is safe and more effective, especially for patients who do not respond well to standard therapy.

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Research cited in this study

10 / 10 results

Platelet-Rich Plasma with Microneedling in Androgenetic Alopecia: Study of Efficacy of the Treatment and the Number of Sessions Required

research Platelet-Rich Plasma with Microneedling in Androgenetic Alopecia: Study of Efficacy of the Treatment and the Number of Sessions Required

January 2021 in “Journal of Cutaneous and Aesthetic Surgery”

Platelet-rich plasma with microneedling is effective for hair loss, but the number of sessions needed varies.

research Meta-Analysis of Efficacy of Platelet-Rich Plasma Therapy for Androgenetic Alopecia

57 citations, May 2016 in “Journal of Dermatological Treatment”

PRP therapy may effectively treat hair loss, but more research needed.

research The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial

214 citations, September 2015 in “Stem Cells Translational Medicine”

Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.

research Platelet-Rich Plasma as a Potential Treatment for Noncicatricial Alopecias

58 citations, January 2015 in “International Journal of Trichology”

Platelet-rich plasma, which carries growth factors, could be a promising treatment for non-scarring hair loss, promoting hair growth and density with no major side effects.

research Study of Platelet-Rich Plasma Injections in the Treatment of Androgenetic Alopecia Through a One-Year Period

164 citations, January 2014 in “Journal of Cutaneous and Aesthetic Surgery”

PRP injections increase hair density and satisfaction in androgenetic alopecia patients.

research A Randomized Evaluator Blinded Study of Effect of Microneedling in Androgenetic Alopecia: A Pilot Study

136 citations, January 2013 in “International Journal of Trichology”

research Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men

198 citations, October 2011 in “Journal der Deutschen Dermatologischen Gesellschaft”

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

research Efficacy and Safety of Finasteride Therapy for Androgenetic Alopecia

152 citations, October 2010 in “Archives of Dermatology”

Finasteride helps hair growth but may cause sexual side effects.

research Male Androgenetic Alopecia: Population-Based Study in 1,005 Subjects

41 citations, July 2009 in “International Journal of Trichology”

58% of men aged 30-50 have hair loss, with severity increasing with age.

research Diagnosis of Hair Disorders

73 citations, March 2009 in “Seminars in Cutaneous Medicine and Surgery”

The document concludes that accurate diagnosis of hair disorders is crucial and requires a range of diagnostic methods.

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community 2024 Official beginner guide for “I’m losing my hair, what can I do?”

in General 726 upvotes 4 months ago

For hair loss, start with Finasteride, Minoxidil, Ketoconazole shampoo, and Microneedling. For severe cases, consider Dutasteride, oral Minoxidil, or hair transplants.

community When are we getting a cure to hair loss?

in Chat 1 year ago

Potential treatments for hair loss, including Minoxidil, finasteride, RU58841 and various upcoming pharmaceuticals, gene editing and cloning. It is suggested that a cure, if found, would be highly profitable due to the large number of people affected by hair loss globally.

community 21F AGA - 4 month hair growth progress (Minoxidil 5%, finasteride 1mg, theradome LLLT, viviscal vitamins, PRP twice)

in Progress Pictures 256 upvotes 2 years ago

A 21-year-old female shared her 4-month hair growth progress using Minoxidil 5%, finasteride 1mg, Theradome LLLT, Viviscal vitamins, and PRP treatments twice. Commenters praised her progress and discussed other treatments like microneedling, but she noted her dermatologist advised against it due to potential scalp damage.

community What else is good. Besides the big 3.

in Chat 34 upvotes 2 months ago

Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

community Reddit’s amatorial meta analysis of 17 already avaliable hair loss prevention treatments that were found to be effective in clinical studies but are not FDA approved for MPB. PROS and CONS. (2022 Guide if Finasteride and Minoxidil are not working/ give you sides/are not enough) 77 studies linked!

in Research/Science 586 upvotes 2 years ago

The post and conversation are about hair loss treatments that have been found to be effective in studies. There are 19 different treatments mentioned, including oral minoxidil, oral dutasteride, topical finasteride, RU58841, and more. The best treatment for an individual depends on factors like availability, cost, side effects, and personal preferences.

community 1.5 years fin plus almost 3 years min, I think I’ve definitely made progress but I’m still not where I want to be, advice?

in Progress Pictures 130 upvotes 11 months ago

The user has been using finasteride for 1.5 years and minoxidil for almost 3 years for hair loss, and has seen some maintenance of hair but not significant regrowth. Suggestions from others include switching to dutasteride, trying oral minoxidil, and considering microneedling or hair fibers for better appearance.

Related Research

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research Evaluating Treatments for Male Androgenetic Alopecia: Clinical Profile and Comparative Efficacy of Platelet Rich Plasma and Minoxidil with Finasteride

September 2024 in “International Journal of Research in Dermatology”

Combining PRP with minoxidil and finasteride is the most effective treatment for male hair loss.

research Faculty Opinions Recommendation of Topical Finasteride for the Treatment of Male Androgenetic Alopecia and Female Pattern Hair Loss: A Review of the Current Literature

December 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Topical finasteride is promising for hair loss with minimal side effects but needs more research and approval.

research Pharmacological Therapeutics in Androgenetic Alopecia

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Minoxidil and finasteride are effective for treating hair loss, with dutasteride showing potential but with side effects.

research Efficacy of Non-Surgical Treatments for Androgenetic Alopecia: A Systematic Review and Network Meta-Analysis

54 citations, May 2018 in “Journal of The European Academy of Dermatology and Venereology”

Low level laser therapy works best for hair loss, followed by PRP, finasteride, and minoxidil.

Combined Treatment with Oral Finasteride and Topical Minoxidil in Male Androgenetic Alopecia: A Randomized and Comparative Study in Chinese Patients

research Combined Treatment with Oral Finasteride and Topical Minoxidil in Male Androgenetic Alopecia: A Randomized and Comparative Study in Chinese Patients

32 citations, June 2015 in “Dermatologic Therapy”

Finasteride and minoxidil together work best for male hair loss.

A New Topical Formulation of Minoxidil and Finasteride Improves Hair Growth in Men with Androgenetic Alopecia