Morphological Substantiation of Clinical Efficacy of Platelet-Rich Plasma in Males with Androgenic Alopecia

    E. E Pakhomova, Перельсон М Е, I. O. Smirnova, Самойлов В О, I. V. Telichko, Терещенко С Н
    TLDR PRP therapy significantly improves hair growth and density in men with androgenic alopecia.
    The study investigated the clinical efficacy of platelet-rich plasma (PRP) in treating 22 men with androgenic alopecia. Patients received intradermal PRP injections over 4 sessions at 4-week intervals. Results showed significant improvements: hair density increased by 11%, average hair diameter by 10%, and a 14% decrease in the proportion of vellus hair. Histological analysis revealed a 148% increase in hair follicle density at the bulb level and a 65% increase at the sweat gland level. Additionally, there was a 47% reduction in telogen hair. These findings indicated that PRP therapy led to significant morphofunctional changes in hair follicles, supporting its clinical efficacy in treating androgenic alopecia.
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