Morphological Substantiation of Clinical Efficacy of Platelet-Rich Plasma in Males with Androgenic Alopecia

December 2018 in “ Вестник Российской Военно-медицинской академии ”

E. E Pakhomova, Перельсон М Е, I. O. Smirnova, Самойлов В О, I. V. Telichko, Терещенко С Н

platelet-rich plasma androgenic alopecia intradermal PRP injections hair density hair diameter vellus hair hair follicle density telogen hair PRP

TLDR PRP therapy significantly improves hair growth and density in men with androgenic alopecia.

The study investigated the clinical efficacy of platelet-rich plasma (PRP) in treating 22 men with androgenic alopecia. Patients received intradermal PRP injections over 4 sessions at 4-week intervals. Results showed significant improvements: hair density increased by 11%, average hair diameter by 10%, and a 14% decrease in the proportion of vellus hair. Histological analysis revealed a 148% increase in hair follicle density at the bulb level and a 65% increase at the sweat gland level. Additionally, there was a 47% reduction in telogen hair. These findings indicated that PRP therapy led to significant morphofunctional changes in hair follicles, supporting its clinical efficacy in treating androgenic alopecia.

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