research Loss of Myeloid Mcpip1 Suppresses Hair Growth and Development of Epidermal Papilloma of the Skin
Removing MCPIP1 from myeloid cells in mice leads to hair loss and prevents skin tumors but causes pigmented spots.
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research Molecular Genetics of Alopecias
Scientists have found specific genes linked to different hair loss conditions, which could lead to new treatments.
research Mesenchymal Stem Cells Antagonize IFN-Induced Proinflammatory Changes and Growth Inhibition Effects via Wnt/β-Catenin and JAK/STAT Pathway in Human Outer Root Sheath Cells and Hair Follicles
Mesenchymal stem cells may help treat hair loss by improving hair cell growth and reducing inflammation.
research Generating Detailed Intercellular Communication Patterns in Psoriasis at the Single-Cell Level Using Social Networking, Pattern Recognition, and Manifold Learning Methods to Optimize Treatment Strategies
New insights into cell communication in psoriasis suggest innovative drug treatments.
research Neutrophil Elastase Is Critical In Linear IgA Bullous Dermatosis In Mice
CD8+ T cells attack hair follicle stem cells, causing scarring and hair loss.
research Wound-Induced Hair Follicle Neogenesis as a Promising Approach for Hair Regeneration
Hair can regrow after significant damage through a process similar to how it forms before birth, involving stem cells and various cell types and signals. This could be a new way to prevent scarring and promote hair growth.
research Nerve Growth Factor and Burn Wound Healing: Update of Molecular Interactions With Skin Cells
Nerve growth factor helps improve healing time and scar quality in burn wounds.
research Faculty Opinions Recommendation of Hidradenitis Suppurativa as a Potential Subtype of Autoinflammatory Keratinization Disease
Hidradenitis suppurativa may be a type of autoinflammatory skin disease linked to gene mutations and immune system issues.
research BJD Snippet
Researchers found certain genes are overactive and others are underactive in men with early balding, which could help create new treatments.
research The Use of Janus Kinase Inhibitors in Alopecia Areata: A Review of the Literature
JAK inhibitors show promise for treating hair loss in alopecia areata but need more clinical trials to confirm safety and effectiveness.
research The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice
Certain proteins, caspases-1 and -11, are important in the early development of skin inflammation in mice.
research Basal Keratinocytes Exhibit Age-Related Epigenetic and Transcriptomic Alterations Resulting in an Altered Metabolic Profile
Aging changes skin cells, leading to different DNA methylation and gene activity, affecting cell metabolism and aging signs.
research Wound Healing and Skin Regeneration
Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
research Corticotropin-Releasing Hormone and the Skin
CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.
research Human Hair Follicle: An Update on Biology and Perspectives in Hair Growth Disorders Treatment
New treatments for hair growth disorders are needed due to limited current options and complex hair follicle biology.
research Lichen Planopilaris and Frontal Fibrosing Alopecia as Model Epithelial Stem Cell Diseases
Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.
research Effects of Mesenchymal Stem Cell Therapy on Alopecia Areata in Cellular and Hair Follicle Organ Culture Models
Mesenchymal stem cell therapy may help treat alopecia areata by promoting hair growth and reducing inflammation.
research Heterogeneity of Neural Crest-Derived Melanocytes
Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.
research LFA-1 Blockade Prevents the Onset of Alopecia Areata in C3H/HeJ Mice
Blocking LFA-1 prevents hair loss in mice.
research Updated Skin Transcriptomic Atlas Depicted by Reciprocal Contribution of Single-Nucleus RNA Sequencing and Single-Cell RNA Sequencing
The research updated the skin cell profile, finding new skin cell markers and showing fibroblasts' key role in skin health.
research Lymphatic Vessel: Origin, Heterogeneity, Biological Functions, and Therapeutic Targets
Lymphatic vessels are essential for health and can be targeted to treat various diseases.
research Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis
TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
research Recent Advances in Exosomal Non-Coding RNA-Based Therapeutic Approaches for Photoaging
New treatments for skin damage from UV light using stem cells and their secretions show promise for skin repair without major risks.
research Increased Expression of TSPEAR in Colorectal Cancer Predicts Poor Prognosis
High TSPEAR levels in colorectal cancer predict worse outcomes.
research Increased Expression of TSPEAR in Colorectal Cancer Predicts Poor Prognosis
High TSPEAR levels in colorectal cancer predict worse outcomes.
research Transcriptome Profiling of Pilosebaceous Units in Male Androgenetic Alopecia Reveals Altered Junctional Networks
Hair loss in male pattern baldness is linked to changes in specific genes and proteins that affect hair growth and scalp health.
research Role of Collagen VI in Peripheral Nerves and Wound-Induced Hair Regrowth
Collagen VI is crucial for nerve function and affects wound-induced hair regrowth.
research Sphingolipid Metabolism Orchestrates the Establishment of the Adult Hair Follicle Stem Cell Niche to Control Skin Homeostasis
A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.
research Pilosebaceous Follicles: Structure, Biochemistry, and Function
Sebaceous glands play a key role in skin health and conditions like acne.
research Comparative Proteomic Analysis in Scar-Free Skin Regeneration in Acomys Cahirinus and Scarring Mus Musculus
The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.