Neutrophil Elastase Is Critical In Linear IgA Bullous Dermatosis In Mice
April 2023
in “
Journal of Investigative Dermatology
”
neutrophil elastase linear IgA bullous dermatosis Primer Cicatricial Alopecias scarring alopecia hair follicle CD8+ T cells epithelial hair follicle stem cells fibrosis CD200R CD200-CD200R signaling pathway immune privilege LPP CCCA DLE scarring hair loss hair follicle stem cells immune system attack lichen planopilaris central centrifugal cicatricial alopecia discoid lupus erythematosus
Studysummary In this study, a mouse model of scarring alopecia demonstrated significantly reduced CD200R expression in affected skin, which may contribute to immune attacks on hair follicles.
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