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GlossaryCD200 receptor (CD200R)

protein on immune cells that regulates immune response

The CD200 receptor (CD200R) is a protein found on the surface of certain immune cells, such as macrophages and dendritic cells. It plays a crucial role in regulating the immune response by interacting with its ligand, CD200, to send inhibitory signals that help prevent excessive inflammation and autoimmunity. This interaction is important in maintaining immune tolerance and has implications in conditions like alopecia, where immune regulation is disrupted.

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Decreased CD200R Expression on Monocyte-Derived Macrophages Correlates with Th17/Treg Imbalance and Disease Activity in Rheumatoid Arthritis Patients

research Decreased CD200R Expression on Monocyte-Derived Macrophages Correlates with Th17/Treg Imbalance and Disease Activity in Rheumatoid Arthritis Patients

31 citations, February 2014 in “Inflammation Research”

Lower CD200R1 on certain immune cells is linked to more severe rheumatoid arthritis and immune imbalance.

research In Vivo Phytotherapy in BALB/c Athymic Nude Mice: Hair Growth Promotion Using Ficus Religiosa L. and Morus Alba L.

1 citations, February 2021 in “Journal of Natural Remedies”

Ficus religiosa and Morus alba extracts improved hair growth and follicle regeneration in mice.

research Understanding Immune Privilege in an Inducible Mouse Model of Primary Cicatricial Alopecia

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

The study found that a key immune pathway protecting hair follicles is reduced in a mouse model of scarring hair loss.

research Neutrophil Elastase Is Critical In Linear IgA Bullous Dermatosis In Mice

April 2023 in “Journal of Investigative Dermatology”

CD8+ T cells attack hair follicle stem cells, causing scarring and hair loss.

research Author Response: Involvement of ILC1-Like Innate Lymphocytes in Human Autoimmunity, Lessons from Alopecia Areata

September 2022

ILC1-like cells may contribute to hair loss in alopecia areata.

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community Fin 3xweek and dermarolling since end of April – October

in Progress Pictures 124 upvotes 2 years ago

A user's progress with finasteride and dermarolling to regrow their hairline, with other users noting the improvement.

community April 15th- August 8th progress. Fin 1mg daily, Min 1-2x a day, keto twice a week and microneedling sometimes

in Progress Pictures 119 upvotes 2 years ago

Treating hair loss with finasteride, minoxidil, keto diet, and microneedling; the user has seen good results but wants to focus more on their temples; another user suggested using an exfoliating comb while shampooing.

community Donald Glover’s (aka Childish Gambino) seamless hair transplant results

in Transplants 1 year ago

Donald Glover's (aka Childish Gambino) hair transplant results, which appear to be moderate with around 1000 grafts. Various users discuss the previous and current appearance of his hairline and speculate that he may have used medications like Minoxidil or finasteride to stabilize before getting a transplant.

community Final Result. 1 Year post Hair Transplant

in Transplants 298 upvotes 2 years ago

A user's experience with a hair transplant procedure and the resulting appearance of their hairline, which included some micro irregularities to make it look natural. Other users asked questions related to cost and safety of similar procedures at different clinics.

community Finally decided to buzz my head after experiencing hair loss since I was 17 (23 now). I think it looks decent, swipe to see what I was rocking before during the pandemic. Who knows maybe I’ll hop on fin but as someone who struggles with chronic fatigue and low test I’m hesitant.

in Shaved/buzzed 326 upvotes 2 years ago

A user's decision to shave their head after experiencing hair loss since the age of 17, and discussion around the potential use of Fin for treating hair loss.

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