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Decreased CD200R Expression on Monocyte-Derived Macrophages Correlates with Th17/Treg Imbalance and Disease Activity in Rheumatoid Arthritis Patients

research Decreased CD200R Expression on Monocyte-Derived Macrophages Correlates with Th17/Treg Imbalance and Disease Activity in Rheumatoid Arthritis Patients

31 citations , February 2014 in “Inflammation Research”

Lower CD200R1 on certain immune cells is linked to more severe rheumatoid arthritis and immune imbalance.

Wnt/β-Catenin and ERK Pathway Activation: The Possible Mechanism of Various LED Light Regulating the Proliferation of Human Outer Root Sheath Cells

research Wnt/β-Catenin and ERK Pathway Activation: The Possible Mechanism of Various LED Light Regulating the Proliferation of Human Outer Root Sheath Cells

May 2017 in “Journal of The American Academy of Dermatology”

LED light helps human hair root cells grow and move by activating certain cell pathways.

research Neutrophil Elastase Is Critical In Linear IgA Bullous Dermatosis In Mice

April 2023 in “Journal of Investigative Dermatology”

CD8+ T cells attack hair follicle stem cells, causing scarring and hair loss.

research Biochemistry of Epidermal Stem Cells

26 citations , July 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects”

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

research Frontal Fibrosing Alopecia Scalp Profiling Links Th1/Th2 And JAK3 Activation With Fibrosis And Loss Of Follicular Stem Cells

April 2019 in “Journal of Investigative Dermatology”

Targeting immune pathways like JAK/STAT may help treat frontal fibrosing alopecia.

View more "cd200-cd200r signaling pathway" in research →

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community My Theory Of Androgenic Alopecia

in Research/Science 19 upvotes 4 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community PP405 Won’t Work: Follicle Is Miniaturized, Fibrosed, And Missing Key Support Cells

in Research/Science 1 month ago

PP405 is ineffective for miniaturized, fibrosed hair follicles in androgenetic alopecia. AMP303 may activate hair follicle stem cells, but minoxidil and finasteride are still the main treatments.