Role of Collagen VI in Peripheral Nerves and Wound-Induced Hair Regrowth
January 2015
collagen VI peripheral nerve function wound-induced hair growth Schwann cells hypermyelination C-fibers nerve conduction velocity sensorimotor dysfunction macrophage migration macrophage polarization nerve regeneration hair follicles Keratin 79 Wnt/beta-catenin signaling pathway collagen 6 nerve function hair growth nerve cells myelination nerve fibers nerve signal speed nerve function issues immune cell movement immune cell function nerve healing hair roots K79 Wnt signaling
Studysummary This study found that collagen VI is crucial for peripheral nerve function and regeneration, and its absence promotes abnormal hair regrowth after skin wounding in mice, revealing potential therapeutic targets for nerve injuries and hair loss.
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