2 citations
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January 2024 in “Pakistan Veterinary Journal” This review highlights the potential of hydrogels in veterinary medicine, emphasizing their advantages over traditional wound dressings and their promising applications in drug delivery and tissue engineering, despite currently limited use in this field.
May 2026 in “Organoid Research” This review highlights recent advancements in the engineering of skin organoids using hydrogels, which improve their structural and functional fidelity by supporting the architecture and integration of vascular and neural components, promising to enhance regenerative medicine, drug discovery, and complex skin disorder studies.
May 2026 in “Organoid Research” This review discusses recent advancements in hair follicle organoid technology for alopecia treatment but presents no new experimental results, emphasizing the potential for clinical applications and drug screening.
This study formulated and evaluated a Hibiscus rosa-sinensis herbal gel, identifying a 20% concentration as superior in physical properties, suggesting its potential as an alternative drug delivery system.
34 citations
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January 2012 in “Journal of Dermatological Science” In this mouse study, researchers found that hydrogen peroxide and monoethanolamine in hair dyes may be key contributors to dermatitis and hair loss due to oxidative stress.
In an animal study, researchers observed that a Chromolaena odorata layered-nitrile rubber transdermal patch significantly improved wound contraction, protein, hexosamine, and uronic acid levels, and collagen deposition in healing excision wounds in rats compared to a control group with an empty patch.
May 2026 in “Iranian journal of pharmaceutical research” This study found that HAMA hydrogels promote faster healing of skin wounds in mice by enhancing the accumulation of anti-inflammatory macrophages and increasing type III collagen in the local wound environment.
March 2026 in “Collagen and Leather” This study found that a newly developed supramolecular FPC hydrogel effectively promotes wound healing through its anti-inflammatory and angiogenic properties, making it a promising material for wilderness first aid due to its storage convenience, sprayability, and ability to speed up wound recovery.
86 citations
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March 2018 in “ACS Biomaterials Science & Engineering” This study found that MDP hydrogel significantly accelerated wound healing and improved tissue formation in diabetic mice compared to a standard clinical hydrogel and control buffer.
1 citations
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June 2025 in “Frontiers in Bioengineering and Biotechnology” This review examines glycopeptide hydrogels as biomimetic materials for tissue regeneration and other biomedical applications, describing their design, properties, and potential uses, and highlighting future advancements in replicating natural tissue environments for precision medicine.
January 2026 in “RSC Advances” The hydrogel helps heal wounds without scars by releasing two drugs gradually.
This research found that keratin hydrogels derived from human hair may support cell viability and proliferation, indicating potential as 2D and 3D soft tissue culture scaffolds.
16 citations
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December 2018 in “ACS Biomaterials Science & Engineering” This research found that a biodegradable fibrous membrane incorporating fibroblast-derived ECM accelerated wound healing and improved neovascularization in a mouse model.
16 citations
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December 2016 in “Skin appendage disorders” This study analyzed patch test results to identify allergens causing scalp contact dermatitis, finding nickel, cobalt, and balsam of Peru among the most common in the patient population.
150 citations
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June 2014 in “Biomaterials” This study found that 'smart' peptide hydrogels improved wound healing in a rat model of partial thickness burns, achieving greater wound closure and faster debridement compared to a standard treatment.
9 citations
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March 2024 in “Journal of Biomaterials Applications” This study developed dissolving microneedles using specific polymers for transdermal delivery of rizatriptan benzoate, demonstrating improved drug skin penetration and significant alleviation of migraine symptoms in vivo compared to passive diffusion, suggesting potential advantages over conventional treatment methods for acute migraine.
9 citations
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April 2025 in “International Journal of Nanomedicine” This research highlights a hydrogel system that could significantly improve diabetic wound healing by releasing ibuprofen to both suppress inflammation and promote tissue regeneration, indicating a strong potential for future clinical use.
61 citations
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November 2020 in “Molecules” This review examines the design strategies for creating conductive hydrogels with adjustable properties for various biomedical applications, highlighting their potential for supporting cell growth, wound healing, drug delivery, tissue regeneration, and biosensing.
18 citations
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February 2025 in “Drug Delivery and Translational Research” This study demonstrated that a new topical treatment using ketotifen-loaded microneedles, designed for prolonged release, significantly reduced inflammatory markers in an animal model of allergic conjunctivitis, suggesting enhanced therapeutic delivery and sustained ocular benefits.
February 2026 in “Bioimpacts” This review discusses advancements and challenges in using 3D bioprinting for diabetic foot ulcer treatments, highlighting potential improvements and existing limitations in replicating skin architecture and clinical application.
In this study, a pH-responsive microneedle patch was developed, showing potential in rat models for treating spinal cord injuries by reducing inflammation, promoting nerve regeneration, and supporting neurogenesis, which contributed to improved motor and neurological recovery.
This research concluded that the novel hydrogel PlacMA, derived from human placenta and curable by visible light, shows promise for cell culture and tissue engineering applications due to its tunable properties.
October 2023 in “Research Square (Research Square)” In this study, researchers found that patients with new-onset mild alopecia areata had higher levels of oxidative stress markers and reduced antioxidant levels compared to healthy individuals, suggesting that oxidative stress might play a role in the condition.
In this study, researchers developed a method using stencils to create controlled stiffness gradients in alginate hydrogels, revealing that stiffer regions within the gels promote deeper invasion by breast cancer cells, facilitating the study of mechanosensitive cellular behaviors.
17 citations
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June 2017 in “Journal of pharmaceutical sciences” This study found that adapalene-loaded nanospheres in a hyaluronic acid gel enhanced skin penetration and were nonirritant, making them potentially suitable for treating acne on oily skin.
January 2026 in “Frontiers in Natural Products” This study found that combining shikimic acid with Prunus mume fruit extract significantly reduces type I 5α-reductase levels in testosterone-stressed skin sebocytes, surpassing the effects of shikimic acid or standard acne treatments alone, and shows promise for stable, non-irritating acne remedies in cosmetic formulations.
1 citations
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December 2024 in “Science, Engineering and Health Studies” This review article discusses recent advances in transdermal drug delivery using nanocomposite systems, which improve drug absorption and release across the skin, allowing both hydrophobic and hydrophilic drugs to be effectively delivered while minimizing side effects.
3 citations
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November 2025 in “Biomimetics” This review discusses the potential of hydrogel-based interventions for radiation-induced skin injury, providing no new clinical results but highlighting their synergistic mechanisms and promise in improving treatment strategies.
March 2026 in “Journal of Nanobiotechnology” This study developed a hydrogel microneedle system combining ginseng-derived exosomes and biomimetic nanoparticles to address oxidative stress, inflammation, and melanocyte deficiency in vitiligo, showing significant repigmentation in mice within 3 weeks by enhancing melanocyte protection and keratinocyte proliferation.
10 citations
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June 2023 in “Preprints.org” This review discusses transdermal drug delivery using hydrogel-forming microneedles and highlights their potential and challenges for clinical application, but it reports no new clinical findings.