TLDR The Chromolaena odorata patch significantly speeds up wound healing.
The study concluded that the Chromolaena odorata-layered nitrile rubber transdermal patch significantly enhances wound healing in rats. Treated wounds showed higher wound contraction, increased levels of proteins, hexosamine, and uronic acid, and improved histological outcomes compared to controls. The patch promoted rapid re-epithelialization, increased fibroblast proliferation, angiogenesis, and denser collagen deposition, leading to faster maturation of collagen from type-III to type-I. These findings suggest that the C. odorata-layered nitrile rubber patch could be developed into an effective wound healing agent for pharmaceutical applications.
1160 citations,
November 2018 in “Physiological Reviews” The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
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January 2015 in “Cold Spring Harbor Perspectives in Medicine” Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.
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October 2021 in “Journal of ethnopharmacology” Indian herbal medicine shows promise for treating skin diseases but needs more research to prove effectiveness.
