TLDR Melasma treatment is difficult, but combination therapies and personalized plans show promise.
Melasma is a complex pigmentary disorder primarily affecting women with certain skin types, characterized by irregular hyperpigmented patches. Its treatment is challenging due to multifactorial causes, resistance to therapies, and high recurrence rates. Traditional treatments like hydroquinone face scrutiny for adverse effects, leading to the exploration of alternatives such as azelaic acid, retinoids, and oral tranexamic acid (TXA), which shows promise in combination therapies. Photoprotection is essential, and personalized treatment plans are crucial for effective management. Recent studies highlight the potential of combination therapies, including procedural interventions like microneedling and laser treatments, to improve outcomes. However, further research is needed to optimize long-term management and minimize side effects.
3 citations,
December 2023 in “Biomedicines” PRP therapy helps skin heal and improve by promoting cell growth and repair.
January 2023 in “Postępy Dermatologii i Alergologii” Azelaic acid treats acne, rosacea, and hyperpigmentation with minimal side effects.
1 citations,
November 2022 in “Journal of Dermatological Treatment” Platelet-rich plasma can increase hair density and may help treat some skin conditions, but it's costly, not FDA-approved, and needs more research.
5 citations,
October 2021 in “Dermatologic Surgery” Platelet-rich plasma (PRP) can significantly improve melasma, a skin pigmentation disorder, but may not add benefits when used with certain other treatments.
January 2017 in “Springer eBooks” The document explains various skin conditions and their treatments.
10 citations,
May 2015 in “International Journal of Women's Dermatology” New treatments for skin and hair disorders in women of color address unique biological differences and include specific acne medications, sunscreens, skin lighteners, and hair care adjustments.
2 citations,
March 2016 in “Obstetrics and Gynecology Clinics of North America” The document says that common skin conditions in adult women can be treated effectively, with acne being the most common and early-detected melanoma having a high survival rate.
January 2018 in “Springer eBooks” Different races and genders have unique skin and hair issues, requiring specialized care and more research for effective treatment.
7 citations,
April 2011 in “Expert review of dermatology” The document concludes that patients with skin of color need specialized dermatological care and education to manage unique skin conditions effectively.
