Unmasking Melasma: Confronting the Treatment Challenges

August 2024 in “ Cosmetics ”

Ena Parać, Zrinka Bukvić Mokoš

melasma hyperpigmented patches hydroquinone azelaic acid retinoids oral tranexamic acid photoprotection microneedling laser treatments TXA

From the encyclopedia

Hydroquinone →

Azelaic Acid →

acid used for antimicrobial, anti-inflammatory and anti-androgenic properties

Microneedling →

technique to create small wounds in skin to activate collagen production and hair growth

Studysummary This review summarizes current melasma treatments, emphasizing the need for tailored, long-term management strategies that integrate photoprotection and address various pathogenic mechanisms.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

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Research cited in this study

6 / 6 results

research Platelet-Rich Plasma in Dermatology: Cellular and Molecular Mechanisms of Action

3 citations , December 2023 in “Biomedicines”

This review discusses the mechanisms and potential benefits of platelet-rich plasma therapy for various skin conditions and reports no new clinical findings.

research The Multiple Uses of Azelaic Acid in Dermatology: Mechanism of Action, Preparations, and Potential Therapeutic Applications

January 2023 in “Postępy Dermatologii i Alergologii”

This review provides an overview of azelaic acid's dermatological uses, mechanisms, and its potential in skin cancer treatment, but reports no new clinical results.

research Decrypting the Potential of Nanotechnology-Based Approaches as Cutting-Edge for Management of Hyperpigmentation Disorder

26 citations , December 2022 in “Molecules”

This review discusses various nanotechnology-based strategies for managing melasma and reports no new clinical results, highlighting the potential of innovative drug delivery systems in treating hyperpigmentation.

research A Comprehensive Review of Platelet-Rich Plasma for the Treatment of Dermatologic Disorders

1 citations , November 2022 in “Journal of Dermatological Treatment”

This review discusses the use of platelet-rich plasma for various dermatologic conditions but reports inconsistent evidence and a lack of standardized protocols; patients often report high satisfaction despite mixed clinical outcomes.

research Platelet-Rich Plasma in Melasma: A Systematic Review

5 citations , October 2021 in “Dermatologic Surgery”

This review found that platelet-rich plasma shows potential in improving melasma, though its overall benefit varies across different treatment methods and may not enhance results when combined with certain other treatments.

research The Versatility of Azelaic Acid in Dermatology

56 citations , July 2020 in “Journal of Dermatological Treatment”

This review found the strongest evidence supporting azelaic acid's use in treating rosacea, with somewhat less evidence for its effectiveness in melasma and acne vulgaris, and weaker support for its use in conditions like hidradenitis suppurativa and keratosis pilaris.