TLDR Different hair protein amounts change the strength of keratin/chitosan gels, useful for making predictable tissue engineering materials.
The study investigated the impact of different hair protein fractions on the properties of keratin/chitosan hydrogels, which are used in tissue engineering. Specifically, it looked at how varying the ratios of keratin-associated proteins (KAPs) and keratin intermediate filaments (KIFs) within the hydrogel affected its mechanical strength. The study found that by adjusting the KAPs/KIFs ratios, the compressive and tensile modulus of the hydrogel could be controlled, leading to more consistent gel properties. This suggests a method for preparing keratin/chitosan hydrogels with predictable characteristics, which is beneficial for their application in tissue engineering.
8 citations
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June 2020 in “Colloids and surfaces. B, Biointerfaces” Heating hair proteins changes their structure and may improve their blood clotting ability.
25 citations
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May 2019 in “Heliyon” Hair treatments cause significant structural changes, especially with excessive heat, regardless of ethnicity.
27 citations
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April 2018 in “Artificial Cells Nanomedicine and Biotechnology” Recombinant human hair keratin proteins can effectively stop bleeding.
14 citations
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April 2016 in “PloS one” The KRTAP11-1 gene promoter is crucial for specific expression in sheep wool cortex.
75 citations
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September 2015 in “Acta biomaterialia” Alkylation of human hair keratin allows for adjustable drug release rates in hydrogels for medical use.
47 citations
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September 2011 in “Acta biomaterialia” Protein composition greatly affects the function of keratin biomaterials.
517 citations
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February 2010 in “Materials” Keratin from hair and wool is used in medical materials for healing and drug delivery.
Human hair keratins can self-assemble and support cell growth, useful for biomedical applications.
517 citations
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February 2010 in “Materials” Keratin from hair and wool is used in medical materials for healing and drug delivery.
Keratin hydrogels from human hair show promise for tissue engineering and regenerative medicine.
8 citations
,
June 2020 in “Colloids and surfaces. B, Biointerfaces” Heating hair proteins changes their structure and may improve their blood clotting ability.
47 citations
,
September 2011 in “Acta biomaterialia” Protein composition greatly affects the function of keratin biomaterials.
