September 2014 in “Springer eBooks” Aging causes hair to gray and thin, with the timing of graying varying by race, and factors like oxidative stress and genetics can lead to hair loss.
December 2023 in “Scientific Reports” Scientists created cell lines from balding patients and found that cells from the front of the scalp are more affected by hormones that cause hair loss than those from the back.
30 citations,
April 2018 in “Experimental Dermatology” The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.
28 citations,
April 2023 in “Stem cell research & therapy” Tiny vesicles from stem cells could be a new treatment for healing wounds.
August 2020 in “Research Square (Research Square)” Oxygen levels affect hair growth and color cells differently when they interact directly.
152 citations,
December 2003 in “Micron” As people age, their hair follicles produce less pigment, leading to gray and white hair, due to factors like reduced enzyme activity and damage to melanocyte DNA.
3 citations,
December 2003 in “Micron” The book "Hair Science and Technology" provides a deep understanding of hair biology and genetics, discusses hair growth, density, and diseases, and offers methods for managing hair loss and caring for hair growth.
September 2019 in “Journal of Investigative Dermatology” PCE-DP brightens skin and promotes hair growth by enhancing cell growth and reducing melanin uptake.
8 citations,
May 2017 in “Chinese Journal of Integrative Medicine” Miscanthus sinensis flower extract may help promote hair growth and prevent hair loss.
99 citations,
September 2007 in “The American journal of pathology” Chemotherapy damages hair follicles, causing hair loss and other cellular changes.
17 citations,
February 2019 in “PubMed” Stem cells can help regenerate hair follicles.
25 citations,
November 2012 in “Phytotherapy Research” Crataegus pinnatifida extract may help increase hair growth and thickness in mice.
38 citations,
April 2016 in “Experimental Dermatology” The document concludes that understanding hair follicle cell cycles is crucial for hair growth and alopecia research, and recommends specific techniques and future research directions.
124 citations,
January 2012 in “Journal of Allergy and Clinical Immunology” Endocannabinoids help control mast cell activity in human skin.
36 citations,
October 1996 in “Dermatologic Clinics” Mice are useful for researching human hair loss and testing treatments, despite some differences between species.
3 citations,
July 2023 in “Biomolecules” B2m-free HLA variants may be a new class of HLA important in immune responses and diseases.
March 2024 in “Stem cell research & therapy” Human dental pulp stem cell-conditioned medium, especially from hypoxic conditions, may help treat chemotherapy-induced hair loss and does not increase cancer risk.
October 2023 in “Applied sciences” Iris germanica rhizome-derived exosomes help protect skin cells from oxidative stress and aging.
106 citations,
March 2014 in “BioEssays” We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
3 citations,
October 2007 in “Expert Review of Dermatology” Hair ages due to various factors and treatments like minoxidil and finasteride can help, but more research and better public awareness are needed.
August 2017 in “Journal of epidemiological research” Cancer rates are increasing in developed countries, with estrogen, aging, low vitamin D3, and HPV infection as common causes.
6 citations,
February 2014 in “Human & experimental toxicology” Testosterone injections can cause skin darkening and thickening.
5 citations,
July 2018 in “Experimental Dermatology” The "Punch Assay" can regenerate hair follicles efficiently in mice and has potential for human hair regeneration.
5 citations,
February 2021 in “Gels” HYDRO DELUXE BIO hyaluronic acid hydrogel is compatible with skin cells, may reduce inflammation, promote blood vessel growth, and protect against oxidative stress, suggesting it could help revitalize hair follicles.
August 2023 in “Military Medical Research” Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
92 citations,
September 2013 in “Journal of Investigative Dermatology” BMAL1 and Period1 genes can influence human hair growth.
35 citations,
January 2020 in “Skin Pharmacology and Physiology” The review concluded that keeping the hair-growing ability of human dermal papilla cells is key for hair development and growth.
43 citations,
October 2005 in “Molecular and cellular endocrinology” Hair melanocytes help the skin respond to stress and regulate hair pigmentation.
Ganoderma lucidum extract may help treat stress-related hair loss.
86 citations,
June 2017 in “Stem cell investigation” Stem cells from hair follicles can safely treat hair loss.