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Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

New research shows that skin diversity is influenced by different types of dermal fibroblasts and their development, especially involving the Wnt/β-catenin pathway.

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.

Natural skincare products may help reduce sun damage and support the skin's daily cycle.

Genomic research can help improve the quality and production of natural fibers in animals.

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

Skin cysts might help advance stem cell treatments to repair skin.

Scientists turned mouse skin cells into hair-inducing cells using chemicals, which could help treat hair loss.

Higher miR-34a levels and the A variant of the MIR-34A gene are linked to increased risk and severity of alopecia areata.

Exosomes could be a promising way to help repair skin and treat skin disorders.

Melatonin, the sleep hormone, can help treat skin conditions like dermatitis, hyperpigmentation, and scalp disorders, and may also aid in skin aging prevention and regeneration. However, it's not recommended for asthma due to its pro-inflammatory effect.

Acne treatment with isotretinoin increases the presence of p53, a protein, in skin and oil glands, which may help reduce acne severity.

New small molecule drugs could help treat hair loss.

Maxillariinae orchids contain 62 compounds with potential health benefits, including treating skin conditions and diseases like cancer and diabetes.

Lotion with fucoidan from brown seaweed improved skin and reduced allergy symptoms in mice with dermatitis.

Androgenetic alopecia in men is genetic and linked to health issues like obesity and heart disease, with treatments including minoxidil, finasteride, and hair transplants.

Exosomal miRNAs from stem cells can help improve skin health and delay aging.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

CRISPR/Cas9 has improved precision and control but still faces clinical challenges.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Studying premature aging syndromes helps understand human aging and suggests potential treatments.

Increasing PBX1 reduces aging and cell death in hair follicle stem cells by boosting SIRT1 and lowering PARP1 activity.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.

Runx genes are important for stem cell regulation and their roles in aging and disease need more research.

The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.

PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.

Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.