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Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Fat-related cells are important for initiating hair growth.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.

Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

Fat cells help recruit healing cells and build skin structure during wound healing.

Nerves are crucial for the regeneration of various body parts in many animals.

Different types of skin cells play specific roles in development, healing, and cancer.

Certain cells from hair follicles can create new hair and contribute to hair growth when implanted in mice.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Sebocytes play a key role in controlling androgen levels in human skin.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Androgens can help prevent memory problems caused by apoE4.

Stem cell niches support, regulate, and coordinate stem cell functions.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Bioprinting could improve wound healing but needs more development to match real skin.