Gelatin-Chondroitin-6-Sulfate-Hyaluronic Acid Scaffold Seeded with Vascular Endothelial Growth Factor 165 Modified Hair Follicle Stem Cells as a Three-Dimensional Skin Substitute

    October 2014 in “ Stem cell research & therapy ”
    Renfu Quan, Xuan Zheng, Shichao Xu … Disheng Yang
    Studysummary This study found that using 3D Gel-C6S-HA scaffolds seeded with VEGF165-modified rat hair follicle stem cells enhanced angiogenesis and vascularization in tissue-engineered skin, improving wound healing.
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    Research cited in this study 6

    1. Differentiation of Human Hair Follicle Stem Cells Into Endothelial Cells Induced by Vascular Endothelial and Basic Fibroblast Growth Factors Molecular Medicine Reports · 2013
    2. Human Hair Follicle Stem Cell Differentiation Into Contractile Smooth Muscle Cells Is Induced by Transforming Growth Factor-β1 and Platelet-Derived Growth Factor BB Molecular Medicine Reports · 2013
    3. Adult Bone-Marrow-Derived Mesenchymal Stem Cells Contribute to Wound Healing of Skin Appendages Cell and Tissue Research · 2006
    4. Isolation of a Novel Population of Multipotent Adult Stem Cells from Human Hair Follicles American Journal Of Pathology · 2006
    5. Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis Cell · 2000
    6. Artificial Skin for Wound Healing Clinics in Dermatology · 1994