Feasibility of Repairing Full-Thickness Skin Defects by iPSC-Derived Epithelial Stem Cells Seeded on a Human Acellular Amniotic Membrane

    May 2019 in “ Stem cell research & therapy ”
    Huateng Zhou, Lixiang Wang, Cui Zhang … Renfu Quan
    Studysummary This study found that combining a human acellular amniotic membrane with iPSC-derived epithelial stem cells effectively repaired skin defects and promoted hair follicle formation in nude mice.
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    Research cited in this study 5

    1. Gelatin-Chondroitin-6-Sulfate-Hyaluronic Acid Scaffold Seeded with Vascular Endothelial Growth Factor 165 Modified Hair Follicle Stem Cells as a Three-Dimensional Skin Substitute Stem cell research & therapy · 2014
    2. Dermal Papilla Cells Improve Wound Healing and Generate Hair Bud-Like Structures in Grafted Skin Substitutes Using Hair Follicle Stem Cells Stem Cells Translational Medicine · 2014
    3. Generation of Folliculogenic Human Epithelial Stem Cells from Induced Pluripotent Stem Cells Nature communications · 2014
    4. Differentiation of Mouse Induced Pluripotent Stem Cells into a Multipotent Keratinocyte Lineage ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2010
    5. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007