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    Glossary Hair Shaft Elongation

    process of hair growing longer from the scalp

    Hair Shaft Elongation refers to the process by which the visible part of the hair, known as the hair shaft, grows longer. This occurs as cells in the hair follicle divide and push the older cells upward, causing the hair to extend out from the scalp. This process is influenced by various factors including genetics, nutrition, and overall health.

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    1. Dihydrotestosterone-Inducible IL-6 Inhibits Elongation of Human Hair Shafts by Suppressing Matrix Cell Proliferation and Promotes Regression of Hair Follicles in Mice Journal of Investigative Dermatology · 2011 · 173 citations
    2. Differential effects of caffeine on hair shaft elongation, matrix and outer root sheath keratinocyte proliferation, and transforming growth factor‐β2/insulin‐like growth factor‐1‐mediated regulation of the hair cycle in male and female human hair follicles<i>in vitro</i> British Journal of Dermatology · 2014 · 60 citations
    3. l-Ascorbic acid 2-phosphate promotes elongation of hair shafts via the secretion of insulin-like growth factor-1 from dermal papilla cells through phosphatidylinositol 3-kinase 2009 · 34 citations
    4. Enhancement of In Vitro Hair Shaft Elongation in Follicles Stored in Buffers That Prevent Follicle Cell Apoptosis Dermatologic Surgery · 2004 · 10 citations
    5. Vitamins and their derivatives synergistically promote hair shaft elongation ex vivo via PlGF/VEGFR-1 signalling activation Journal of dermatological science · 2022 · 1 citations
    6. PD-L1 vNAR promotes hair growth by modulating hair shaft elongation through activating the leptin-STAT3 signaling Cell Communication and Signaling · 2026
    7. MLPH-mediated activation of dermal papilla IGF-1 signaling drives human hair shaft elongation and anagen induction Biomedicine & Pharmacotherapy · 2026
    8. 1376 Dermal white adipose tissue enhances proliferation, pigmentation and hair shaft elongation in human hair follicles ex vivo Journal of Investigative Dermatology · 2018
    9. Enhancement of In Vitro Hair Shaft Elongation in Follicles Stored in Buffers That Prevent Follicle Cell Apoptosis Dermatologic Surgery · 2004
    10. Extensive Hair-Shaft Elongation by Isolated Mouse Whisker Follicles in Very Long-Term Gelfoam® Histoculture PLoS ONE · 2015 · 5 citations
    11. Control of Human Hair Growth by Neurotrophins: Brain-Derived Neurotrophic Factor Inhibits Hair Shaft Elongation, Induces Catagen, and Stimulates Follicular Transforming Growth Factor β2 Expression Journal of Investigative Dermatology · 2005 · 64 citations
    12. Tectoridin Stimulates the Activity of Human Dermal Papilla Cells and Promotes Hair Shaft Elongation in Mouse Vibrissae Hair Follicle Culture Molecules · 2022 · 7 citations
    13. Human hair follicles display a functional equivalent of the hypothalamic‐pituitary‐adrenal (HPA) axis and synthesize cortisol The FASEB Journal · 2005 · 489 citations
    14. Skin and hair on-a-chip: in vitro skin models versus ex vivo tissue maintenance with dynamic perfusion Lab on a Chip · 2013 · 208 citations
    15. A Hot New Twist to Hair Biology ˜The œAmerican journal of pathology (Print) · 2005 · 174 citations
    16. Analysis of Apoptotic Cell Death in Human Hair Follicles In Vivo andIn Vitro Journal of Investigative Dermatology · 1998 · 140 citations
    17. Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression American Journal of Pathology · 2006 · 128 citations
    18. Hair growth promoting effects of adipose tissue-derived stem cells Journal of Dermatological Science · 2009 · 81 citations
    19. Thyrotropin releasing hormone (TRH): a new player in human hair‐growth control ˜The œFASEB journal · 2009 · 72 citations
    20. Spermidine Promotes Human Hair Growth and Is a Novel Modulator of Human Epithelial Stem Cell Functions PLOS ONE · 2011 · 61 citations
    21. Growth of secondary hair follicles of the Cashmere goat in vitro and their response to prolactin and melatonin. PubMed · 1994 · 56 citations
    22. Profiling the Response of Human Hair Follicles to Ultraviolet Radiation Journal of Investigative Dermatology · 2009 · 53 citations
    23. The Basic Mechanism of Hair Growth Stimulation by Adipose-derived Stem Cells and Their Secretory Factors Current Stem Cell Research & Therapy · 2017 · 52 citations
    24. Estrogens and the hair follicle. Ostrogene und der Haarfollikel Journal der Deutschen Dermatologischen Gesellschaft · 2004 · 50 citations
    25. Induction of Hair Growth by Insulin-Like Growth Factor-1 in 1,763 MHz Radiofrequency-Irradiated Hair Follicle Cells PLoS ONE · 2011 · 39 citations
    26. The hair growth promoting effect of ascorbic acid 2-phosphate, a long-acting Vitamin C derivative Journal of Dermatological Science · 2006 · 33 citations
    27. A role of placental growth factor in hair growth Journal of dermatological science · 2014 · 31 citations
    28. Role of Arachidonic Acid in Promoting Hair Growth 2016 · 29 citations
    29. L‐Carnitine–L‐tartrate promotes human hair growth <i>in vitro</i> Experimental Dermatology · 2007 · 26 citations
    30. Icariin promotes mouse hair follicle growth by increasing insulin-like growth factor 1 expression in dermal papillary cells Clinical and Experimental Dermatology · 2017 · 22 citations