2 citations
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July 2023 in “International Journal of Molecular Sciences” This study found that applying a formulation derived from Bacopa procumbens significantly promoted hair growth, pigmentation, and follicular cycle acceleration in mice compared to minoxidil, potentially offering a new therapeutic approach for hair health.
2 citations
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July 2023 in “Animals” In this study, researchers investigated a regulatory network in cashmere goat embryos and found that fibroblast growth factor 10, alongside non-coding RNAs, significantly influences hair follicle cell proliferation, offering insights into the biology of hair follicles in cashmere goats.
1 citations
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September 2025 in “International Journal of Molecular Sciences” This study found that primary stem cells from concentrated growth factor can differentiate into adipogenic, endothelial, and neuronal lineages in vitro, suggesting potential for use in regenerative therapies.
The researchers reported that PEG-FGF2 conjugates, particularly Compound 6, significantly enhanced stability, proliferation, migration, and wound healing activity compared to native FGF2, despite some reduction in bioactivity near crucial binding domains.
April 2026 in “Journal of Dermatological Treatment” This study concluded that in female pattern hair loss patients, CGF and i-PRF treatments were more effective than PRP in increasing target area hair count, with i-PRF having the lowest adverse event rate.
October 2023 in “Current Issues in Molecular Biology” In this study, researchers observed that the YH complex, made from Astragalus membranaceus and Cinnamomum cassia, promoted hair regrowth and increased hair shaft thickness in mice, potentially through increased growth factors and Wnt/β-catenin signaling, suggesting its use for treating various forms of hair loss.
August 2023 in “Journal of analytical & pharmaceutical research” In this study, microneedle-assisted human basic fibroblast growth factor therapy was reported to significantly improve hair regeneration in both male and female patients with androgenetic alopecia, alopecia areata, and telogen effluvium, showing greater effectiveness in males.
This study found that garlic exosomes induced hair growth in rats by increasing anagen follicle counts and activating multiple signaling pathways, including Wnt-1, β-catenin, and TGF-β1.
July 2023 in “Research Square (Research Square)” In this study conducted on rabbits, conventional blood treated with 120% sodium citrate was observed to achieve the highest platelet recovery and enrichment coefficient, while altering sodium citrate concentrate affected levels of growth factors PDGF and TGF-β1 after plasma activation.
July 2023 in “Indian Journal of Animal Health” This study found that fibroblast growth factor 5 may enhance Cashmere goat hair growth by altering the expression of specific genes related to keratin and keratin-associated proteins.
May 2023 in “Journal of Cosmetic Dermatology” This prospective randomized controlled trial found that combining platelet-rich plasma plus basic fibroblast growth factor injections with topical minoxidil significantly improves hair count and growth rate in androgenetic alopecia patients compared to either treatment alone.
June 2022 in “International journal of drug delivery technology” This study investigated the hair growth-promoting effect of topical nebivolol cream in mice, but the abstract does not provide specific results or conclusions.
August 2019 in “Research Square (Research Square)” This study explored how long non-coding RNA mediates the effects of FGF5 on the hair follicle development and villus growth of Liaoning cashmere goats.
June 2014 in “Journal of biomedical research” This study found that ethanol extract and an ethyl acetate fraction of Sargassum fusiforme promoted hair regrowth in C57BL/6 mice and stimulated expression of hair growth-related genes in both in vitro and in vivo models.
This study found that Chrysanthemum zawadskii extract may promote hair growth by inducing an earlier conversion of telogen to anagen and increasing the proliferation of dermal papilla cells in mice and human hair follicle cultures.
30 citations
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August 2009 in “Journal of the American Academy of Dermatology” This study found that while bimatoprost was safe for 16 weeks, it was not effective for eyelash growth in patients with significant loss due to alopecia areata, though some with less loss experienced growth.
4 citations
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January 2020 in “Lasers in Surgery and Medicine” This study found that combining a 308-nm excimer lamp with minoxidil led to significant hair regrowth in alopecia areata patients, with side effects like hyperpigmentation being tolerable.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers identified a gene regulatory network in Arabidopsis that controls root hair growth under low-temperature conditions, revealing specific transcription factors and downstream targets that contribute to this growth response despite overall plant development being halted.
397 citations
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February 2004 in “British Journal of Dermatology” This article reviews the mechanisms by which minoxidil stimulates hair growth and reports no new clinical findings.
87 citations
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March 2005 in “Journal of Dermatological Science” This study found that the extract of Asiasari radix may promote hair growth in mice by enhancing protein synthesis, cell proliferation, and growth factor expression.
27 citations
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June 2023 in “Nature” In this study using genetic mouse models, researchers discovered that senescent melanocytes in nevi secrete osteopontin, which activates hair stem cells, enhancing hair growth; this process is mirrored in human hairy nevi, suggesting a potential therapeutic target for regenerative disorders.
22 citations
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July 2019 in “PLOS ONE” This study found that lymphatic vessels promote hair follicle growth in mice and may represent new therapeutic targets for hair loss conditions.
17 citations
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February 2015 in “International Journal of Molecular Sciences” This study found that keratinocyte stem/progenitor cell-conditioned medium significantly enhanced hair growth in mice and increased the proliferation of human hair follicle cells.
17 citations
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May 2014 in “Naunyn-Schmiedeberg's Archives of Pharmacology” In this study, 7-phloroeckol, derived from marine brown algae, was found to promote hair growth by increasing cell proliferation and hair shaft elongation in cultured human hair follicles.
16 citations
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April 2017 in “Journal of Cosmetic Dermatology” This study found that fig leaf extract significantly downregulated inflammatory and androgenic gene expression in vitro, suggesting potential topical benefits for certain skin disorders.
10 citations
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April 2019 in “Journal of Analytical Science and Technology” In this study, hydrolysates of lactic acid bacteria were found to enhance hair growth in C57BL/6 male mice more effectively than 5% minoxidil.
8 citations
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April 2020 in “Journal of Ethnopharmacology” This review assessed experimental studies on herbs used for alopecia, identifying potential mechanisms involving hair cycle management and keratinocyte processes, but highlighted a need for improved evidence on quality control and toxicity of these herbal treatments.
8 citations
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June 2019 in “Journal of Ginseng Research” This study found that a gintonin-enriched fraction from ginseng promoted hair growth in mice by stimulating dermal papilla cell proliferation and increasing hair follicles and weight.
6 citations
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February 2018 in “PLOS ONE” This study found that insect wax can significantly promote hair growth in mice in a way that is comparable to minoxidil, likely due to the upregulation of VEGF expression.
4 citations
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April 2012 in “Asian-australasian Journal of Animal Sciences” This study found that applying deer antler extract to rat skin wounds enhanced hair growth and increased IGF-I expression, suggesting potential use in hair growth products.