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This narrative review explores the molecular mechanisms driving skin development and their role in skin diseases, emphasizing how disruptions in these pathways can lead to conditions like congenital disorders and cancers, potentially guiding new targeted therapies.

iNKT cells help develop and maintain healthy skin in young mice.

This study demonstrated that hyaluronan gel is a promising biomaterial for 3-D in vitro culture of mouse ovarian follicles, supporting the production of fertilizable metaphase II oocytes.

This study found that soluble CD83 (sCD83) accelerated chronic and hard-to-heal wound healing and improved inflammatory and pro-resolving cytokine profiles, suggesting potential for therapeutic use.

In this retrospective review, the author discusses key discoveries in understanding androgen excess disorders like PCOS, focusing on genetic and molecular insights gained from 1965 to 2015.

This study found that exposure to certain elements during pregnancy, measured in maternal hair, was associated with increased risk of gestational diabetes and potential impacts on infant neurodevelopment, with elements like Ta, Re, and Se posing the highest risk for gestational diabetes.

This study concluded that dietary changes alter serum progesterone and estradiol levels in late gestation ewes, likely due to metabolism rather than changes in placental steroid synthesis.

This review discusses phenotypic differences in testosterone production between mice and humans with HSD17B3 deficiency and reports no new findings; the authors highlight potential pathways and enzymes involved in testosterone synthesis.

This review compiles EV proteomics data and reports that while MSC-derived EVs show promise in skin therapeutics, variability in protein cargo highlights the need for standardized methodologies in understanding process impacts.

This review explores the different types of hydrogels used to repair diabetic ulcers, the mechanisms involved, and the limitations in developing these technologies for clinical use, but it reports no new clinical results.

This study revealed that deleting EZH2 in mesenchyme-derived cells of the female reproductive tract led to impaired uterine gland development and pregnancy loss in mice, highlighting EZH2's crucial role in fertility.

This review discusses the role of stem cells and tissue engineering in regeneration and transplantation, emphasizing the need for advanced technologies to improve treatments for injuries and disabilities, but reports no new results.

In this review, researchers evaluated sericin-based drug delivery systems for antimicrobial, anticancer, and neurodegenerative treatments, highlighting its potential benefits and challenges related to molecular variability and formulation stability, suggesting future focus on optimizing extraction and integration with advanced biomedical technologies.

This review highlights recent research using single-cell RNA sequencing and machine learning in wound healing, revealing significant insights into fibroblast diversity, immune cell dynamics, and the spatial organization of cells, which may transform therapeutic strategies for chronic wounds, fibrosis, and tissue regeneration.

This review highlights advancements in applying single-cell sequencing to cattle, sheep, and goats, noting its potential to elucidate cellular diversity and improve traits affecting livestock health and productivity, despite challenges in cell population annotation and spatial resolution in these species.

This study found that using a shampoo containing heat-killed probiotics, GMNL-653, led to decreased dandruff and sebum production and increased hair growth in human participants, with observed microbiota shifts including changes in M. globosa and M. restricta abundance.

In this study, researchers found that specific miRNAs may regulate cashmere fiber traits in goats by targeting genes related to hair follicle activities, with significant expression differences between breeds.

In this study, researchers identified key miRNAs and target genes involved in hair follicle development in Merino sheep, providing insights that could aid in improving sheep breeding for wool quality.

This study found that the green alga Botryococcus terribilis and its novel compounds significantly promoted hair growth marker gene expression in hair follicle dermal papilla cells without cytotoxic effects.

This study investigated transcription factors in human trophectoderm cells during development, finding that GATA2 and GATA3 are essential for transforming stem cells into induced trophoblast stem cells, which display characteristics similar to placental progenitor cells, offering new methods for modeling placental-associated diseases.

This review discusses the roles of resident macrophages in the liver and lung, emphasizing their unique contributions to maintaining tissue homeostasis and the interface between circulation and external environments, but reports no new findings.

This review discusses the various types of stem cells, including their potential applications in therapy, and reports the challenges associated with safe stem cell treatment, with no new clinical results presented.

This article reviews the immunometabolic mechanisms linking polycystic ovary syndrome to infertility and stresses the need for interdisciplinary approaches to treat PCOS-related fertility issues; it reports no new clinical results.

In this study, researchers reported that a newly developed interferon-γ release assay for cell-mediated immunity to SARS-CoV-2 nucleocapsid peptides demonstrated high sensitivity and specificity, making it a robust tool for routine diagnostic tests and potentially useful in predicting clinical outcomes after pathogen re-exposure.

This study found that peach kernel oil extracted via supercritical fluid extraction had higher quality and antioxidant properties than oil obtained by other methods, effectively protecting human hair follicle keratinocytes from oxidative damage.

This study found that platelet-rich fibrin lysates modulate chemokine expression, reducing inflammation in oral squamous carcinoma cells, but increasing expression in primary oral epithelial cells.

This study suggests that Gujian oral liquid may reduce osteoarthritis symptoms by regulating inflammation and catabolism through the TNF-α/NF-kappa B signaling pathway, as confirmed by both in vivo and in vitro experiments.

This study developed immortalized human hair follicle-derived mesenchymal-like stromal cells (iHF-MSCs) as a consistent source of therapeutic secretome, reporting their superior immunomodulatory and regenerative performance, potentially advancing cell-free therapies for inflammation and tissue repair.

This study found that administering minoxidil and PGE₂ to pregnant mice with 22q11.2 deletion syndrome models corrected multiple developmental anomalies, including thymus growth and parathyroid positioning, by targeting prenatal mesenchymal differentiation.

This study examined genetic adaptations in Tibetan sheep through whole-genome resequencing, identifying key genes related to hypoxia tolerance, wool color, and body size. These findings provide a foundation for future molecular breeding strategies to enhance wool quality and adaptive traits in these high-altitude environments.