Soluble CD83 Improves and Accelerates Wound Healing by the Induction of Pro-Resolving Macrophages

    September 2022 in “ Frontiers in Immunology ”
    Dmytro Royzman, Katrin Peckert-Maier, Lena Stich … Alexander Steinkasserer
    Studysummary This study found that soluble CD83 (sCD83) accelerated chronic and hard-to-heal wound healing and improved inflammatory and pro-resolving cytokine profiles, suggesting potential for therapeutic use.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on frontiersin.org →
    Discuss this study in the Community →

    Research cited in this study 10

    1. Hair Follicle Bulge-Derived Stem Cells Promote Tissue Regeneration During Skin Expansion Biomedicine & Pharmacotherapy · 2020
    2. Through the Lens of Hair Follicle Neogenesis: A New Focus on Mechanisms of Skin Regeneration After Wounding Seminars in Cell & Developmental Biology · 2019
    3. Deciphering the Molecular Morphology of the Human Hair Cycle: Wnt Signalling During the Telogen–Anagen Transformation British Journal of Dermatology · 2019
    4. Epidermal Growth Factor Promotes Mesenchymal Stem Cell-Mediated Wound Healing and Hair Follicle Regeneration PubMed · 2017
    5. Wnt and Notch Signaling Pathway Involved in Wound Healing by Targeting c-Myc and Hes1 Separately Stem Cell Research & Therapy · 2015
    6. Wound Healing and Skin Regeneration Cold Spring Harbor Perspectives in Medicine · 2015
    7. Epidermal Stem Cells and Skin Tissue Engineering in Hair Follicle Regeneration World Journal of Stem Cells · 2015
    8. Augmenting Endogenous Wnt Signaling Improves Skin Wound Healing PLoS ONE · 2013
    9. Gsdma3 Is Required for Hair Follicle Differentiation in Mice Biochemical and biophysical research communications · 2010
    10. Tcf3 and Lef1 Regulate Lineage Differentiation of Multipotent Stem Cells in Skin Genes & Development · 2001