The Identification and Characteristics of miRNAs Related to Cashmere Fiber Traits in Skin Tissue of Cashmere Goats

February 2023 in “ Genes ”

Lirong Qiao, Yuanhua Gu, Shiwei Guo, Shiqiang Li, Jiqing Wang, Zhiyun Hao, Yuzhu Luo, Xiu Liu, Shaobin Li, Fangfang Zhao, Mingna Li

This study investigated the role of microRNAs (miRNAs) in cashmere fiber traits by comparing the miRNA expression profiles in the skin tissue of Liaoning cashmere (LC) goats and Ziwuling black (ZB) goats, each with 6 individuals. A total of 1,293 miRNAs were identified, with 112 up-regulated and 32 down-regulated in LC goats compared to ZB goats. The differentially expressed miRNAs were linked to pathways such as Wnt, Notch, and MAPK, which are associated with cashmere fiber performance. An interaction network highlighted 14 miRNAs potentially regulating cashmere fiber traits by targeting genes related to hair follicle activities, providing a basis for further research on miRNA influences in cashmere goats.

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