The Identification and Characteristics of miRNAs Related to Cashmere Fiber Traits in Skin Tissue of Cashmere Goats

February 2023 in “ Genes ”

Lirong Qiao, Yuanhua Gu, Shiwei Guo, Shiqiang Li, Jiqing Wang, Zhiyun Hao, Yuzhu Luo, Xiu Liu, Shaobin Li, Fangfang Zhao, Mingna Li

microRNAs miRNAs Wnt pathway Notch pathway MAPK pathway hair follicle activities

TLDR Certain miRNAs may influence cashmere fiber traits in goats by affecting hair follicle activities.

This study investigated the role of microRNAs (miRNAs) in cashmere fiber traits by analyzing miRNA expression in the skin tissue of Liaoning cashmere (LC) and Ziwuling black (ZB) goats, each with 6 individuals. A total of 1,293 miRNAs were identified, with 144 differentially expressed between the breeds. LC goats showed 112 up-regulated and 32 down-regulated miRNAs compared to ZB goats. These miRNAs are linked to pathways like Wnt, Notch, and MAPK, associated with hair follicle activities and cashmere fiber performance. The study highlights 14 miRNAs that may influence cashmere fiber traits, providing a foundation for further research into miRNA impacts on cashmere quality and quantity.

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