New Insights Into Testosterone Biosynthesis: Novel Observations From HSD17B3 Deficient Mice

    December 2022 in “ International journal of molecular sciences ”
    Ben M. Lawrence, Liza O’Donnell, Lee B. Smith, Diane Rebourcet
    Studysummary This review discusses phenotypic differences in testosterone production between mice and humans with HSD17B3 deficiency and reports no new findings; the authors highlight potential pathways and enzymes involved in testosterone synthesis.
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    Research cited in this study 3

    1. Basics of Androgen Synthesis and Action Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism · 2022
    2. Steroidogenesis of the Testis: New Genes and Pathways Annales d'endocrinologie · 2014
    3. Overexpression of Aldo-Keto Reductase 1C3 in LNCaP Cells Diverts Androgen Metabolism Towards Testosterone Resulting in Resistance to the 5α-Reductase Inhibitor Finasteride The Journal of Steroid Biochemistry and Molecular Biology · 2012