March 2023 in “International Journal of Molecular Sciences” ADSC-Exos with miR-122-5p can help treat hair loss by promoting hair growth.
437 citations,
August 2014 in “Cell metabolism” Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.
23 citations,
December 2017 in “Scientific Reports” ARL15 is important for fat cell development and the release of the hormone adiponectin.
11 citations,
March 2021 in “Journal of Bioscience and Bioengineering” Adding human fat-derived stem cells to hair follicle grafts greatly increases hair growth.
11 citations,
May 2015 in “Stem Cells Translational Medicine” Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.
8 citations,
February 2021 in “Biomolecules & therapeutics” Myristoleic acid helps hair growth by boosting cell growth and recycling processes in hair follicle cells.
1 citations,
March 2024 in “Signal transduction and targeted therapy” NF-κB signaling is crucial in many diseases and can be targeted for new treatments.
1 citations,
August 2022 in “Frontiers in Physiology” Finasteride may help treat kidney disease caused by a high-fat diet by reducing harmful toxins and improving gut bacteria.
July 2024 in “Journal of Nanobiotechnology” Mouse cell exosomes help hair regrowth and wound healing by activating a specific signaling pathway.
February 2023 in “Frontiers in Pharmacology” Water extract of Cacumen Platycladi helps hair growth by activating specific cell pathways.
127 citations,
July 2002 in “EMBO journal” Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.
25 citations,
April 2021 in “The EMBO Journal” Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.
9 citations,
June 2023 in “Cells” Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
9 citations,
January 2018 in “Stem Cells International” Deer antler stem cell fluid helps regenerate tissue better than fat-derived stem cell fluid.
5 citations,
June 2019 in “Journal of lipid research” New probes were created to effectively measure specific enzymes involved in fat metabolism, which could help develop new drugs.
1 citations,
May 2023 in “Frontiers in endocrinology” A new MBTPS2 gene variant disrupts fat metabolism and collagen production, causing Osteogenesis imperfecta.
Certain natural products may help stimulate hair growth by affecting stem cell activity in the scalp.
134 citations,
January 2010 in “Biomedical research” Low oxygen conditions increase the hair-growing effects of substances from fat-derived stem cells by boosting growth factor release.
66 citations,
February 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Adenosine may promote hair growth by increasing FGF-7 levels in dermal papilla cells.
17 citations,
July 2014 in “Expert Opinion on Biological Therapy” The new method for isolating stem cells from fat is simple and effective, producing cells that grow faster and are better for hair regeneration.
5 citations,
February 2022 in “Frontiers in physiology” Hair graying is influenced by factors like nerves, fat cells, and immune cells, not just hair follicles.
1 citations,
December 2023 in “Animals” Winter provides the best fur quality for Rex rabbits due to seasonal changes in specific signaling pathways.
18 citations,
May 2018 in “International Journal of Molecular Sciences” Human body's immune cells are more common in the layer of fat just beneath the skin than in deeper fat layers.
June 2024 in “The Journal of Nutritional Biochemistry” 1,25-(OH)2D3 helps hair grow by blocking certain harmful signals.
56 citations,
July 2014 in “PloS one” SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.
32 citations,
April 2016 in “Journal of Obstetrics and Gynaecology Research” Women with severe types of PCOS are more likely to have metabolic syndrome, and belly fat is a key predictor of this risk.
5 citations,
February 2017 in “Biomolecules & Therapeutics” 4-O-Methylhonokiol helps protect skin cells from growth-stopping effects of a protein by regulating growth-related pathways.
The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.
31 citations,
January 2017 in “Advances in Experimental Medicine and Biology” Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
21 citations,
January 2018 in “Journal of Investigative Dermatology” Rats can't grow new hair follicles after skin wounds, unlike mice, due to differences in gene expression and response to WNT signaling.