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As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.

The conclusion is that the IL-6/STAT3 activation affects p63 expression in healing wounds, which may help in hair follicle regeneration.

Keeping β-catenin levels high in mammary cells disrupts their development and branching.

New genetic locations explain much of hair color variation in Europeans.

Loss of a specific protein in skin cells causes symptoms similar to psoriasis.

Vitamin D receptor is important for regulating hair growth and wound healing in mice.

Epidermal stem cells create and maintain skin structures like hair and nails through specific signaling pathways and vary by location and function.

Current methods can't fully recreate skin and its features, and more research is needed for clinical use.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.

Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.

Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.

Different types of skin on mice have unique chemical profiles related to how they grow and react to stress.

Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.

Epithelial stem cells can adapt and help in tissue repair and regeneration.

Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.

The protein RSL4 is crucial for making root hairs longer by controlling genes related to cell growth.

Chicken feather growth involves specific genes and shares similarities with hair development.

MicroRNAs could improve skin tissue engineering by regulating cells and changing the skin's bioactive environment.

Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.

Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.

Skin organoids from stem cells could better mimic real skin but face challenges.

Skin stem cells are promising for healing wounds and skin regeneration due to their accessibility and regenerative abilities.

Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.

Skin cells release substances important for healing and fighting infection, and understanding these could improve skin disorder treatments.

New research shows that skin diversity is influenced by different types of dermal fibroblasts and their development, especially involving the Wnt/β-catenin pathway.

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.

Zebrafish are useful for studying and developing treatments for human skin diseases.

Lrig1 could be a marker for advanced sebaceous carcinoma.