Generation of Skin Organoids: Potential Opportunities and Challenges

    Hui Sun, Yixuan Zhang, Yumei Li
    TLDR Skin organoids from stem cells could better mimic real skin but face challenges.
    The document "Generation of Skin Organoids: Potential Opportunities and Challenges" discusses the advancements in creating three-dimensional skin organoids from stem cells, which can mimic the structure and function of human skin, including hair follicles and sweat glands. These organoids offer significant potential for disease modeling, drug testing, and regenerative medicine. However, challenges such as replicating the full complexity of human skin, ensuring long-term stability, and achieving vascularization and immune integration remain. The paper emphasizes the need for standardized protocols and further research to overcome these obstacles and fully realize the potential of skin organoids in biomedical research.
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