Regeneration of a Bioengineered 3D Integumentary Organ System from iPS Cells

    April 2019 in “ Nature protocols ”
    Koh-éi Toyoshima, Miho Ogawa, Takashi Tsuji
    Studysummary This study describes a protocol for generating a fully functional 3D integumentary organ system from murine induced pluripotent stem cells, including the formation of hair follicles and sebaceous glands that function in vivo.
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    Research cited in this study 8

    1. Bioengineering a 3D Integumentary Organ System from iPS Cells Using an In Vivo Transplantation Model Science Advances · 2016
    2. Advances in Skin Grafting and Treatment of Cutaneous Wounds Science · 2014
    3. Functional Lacrimal Gland Regeneration by Transplantation of a Bioengineered Organ Germ Nature Communications · 2013
    4. Functional Salivary Gland Regeneration by Transplantation of a Bioengineered Organ Germ Nature Communications · 2013
    5. Fully Functional Hair Follicle Regeneration Through the Rearrangement of Stem Cells and Their Niches Nature Communications · 2012
    6. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    7. Scratching the Surface of Skin Development Nature · 2007
    8. Integument Pattern Formation Involves Genetic and Epigenetic Controls: Feather Arrays Simulated by Digital Hormone Models ˜The œInternational journal of developmental biology · 2004

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    1. Regeneration of a Bioengineered 3D Integumentary Organ System from iPS Cells Nature protocols · 2019