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Prdm1 is necessary for early whisker development in mice but not for other hair, and its absence changes nerve and brain patterns related to whiskers.

Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.

Different types of skin fibroblasts have unique roles in skin health and disease.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

Skin cell behavior is influenced by the tightness of nearby cells, affecting their growth and development.

Current methods can't fully recreate skin and its features, and more research is needed for clinical use.

Skin cysts might help advance stem cell treatments to repair skin.

Stem cells are crucial for wound healing and understanding their role could lead to new treatments, but more research is needed to answer unresolved questions.

Skin organoids from stem cells can help study and treat skin issues but face some challenges.

CD34+ and CD34- melanocyte stem cells have different regenerative abilities.

Scaffoldin helps form hard skin structures in chicken embryos.

Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.

Platelet-rich plasma may improve wound healing by stimulating cell growth and blood vessel formation.

Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.

The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.

MicroRNAs are crucial for skin development, regeneration, and disease treatment.

Creating fully functional artificial skin for chronic wounds is still very challenging.

Neuregulin3 affects cell development in the skin and mammary glands.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

WNT signaling is crucial for skin development and healing.

Fat-derived stem cells show promise for treating skin issues and improving wound healing, but more research is needed to confirm the best way to use them.

Stem cells could potentially rebuild missing structures in wounds, improving facial skin replacement techniques.

PRP may help with aging and osteoarthritis, improving tissue repair and reducing surgery risk.

Choosing the right method to separate skin layers is key for good skin cell research.

The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.

Human dermal stem cells can become functional skin pigment cells.

Epidermal stem cells don't use gap junctions to communicate.

Ectodysplasin signaling is crucial for skin appendage development, requiring specific doses and durations.

WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.

Hormones and stretching both needed for nipple area skin growth in mice.