Search
for

    Glossary DNA damage

    alterations in DNA structure that disrupt normal function

    DNA damage refers to alterations in the DNA structure that can disrupt its normal function. These changes can be caused by various factors, including environmental agents like UV radiation, chemicals, or even normal cellular processes. If not properly repaired, DNA damage can lead to mutations, which may result in diseases such as cancer or contribute to aging.

    Related Terms

    Sort by

    Research 30 of 1000+

    1. Brain and muscle Arnt-like protein-1 (BMAL1) controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis Proceedings of the National Academy of Sciences of the United States of America · 2012 · 221 citations
    2. Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair Experimental dermatology · 2008 · 160 citations
    3. DNA Damage Response Mediates Pressure Overload–Induced Cardiomyocyte Hypertrophy Circulation · 2019 · 42 citations
    4. Androgen Receptor Accelerates Premature Senescence of Human Dermal Papilla Cells in Association with DNA Damage PLOS ONE · 2013 · 30 citations
    5. Exposure to non-ionizing electromagnetic fields emitted from mobile phones induced DNA damage in human ear canal hair follicle cells Electromagnetic biology and medicine · 2018 · 25 citations
    6. DNA Damage-Inducible Transcript 4 Is an Innate Surveillant of Hair Follicular Stress in Vitamin D Receptor Knockout Mice and a Regulator of Wound Re-Epithelialization International journal of molecular sciences · 2016 · 22 citations
    7. Intrinsic ROS Drive Hair Follicle Cycle Progression by Modulating DNA Damage and Repair and Subsequently Hair Follicle Apoptosis and Macrophage Polarization Oxidative Medicine and Cellular Longevity · 2022 · 20 citations
    8. An efficient, non-invasive approach for in-vivo sampling of hair follicles: design and applications in monitoring DNA damage and aging Aging · 2021 · 12 citations
    9. PBX1 Attenuates Hair Follicle-Derived Mesenchymal Stem Cell Senescence and Apoptosis by Alleviating Reactive Oxygen Species-Mediated DNA Damage Instead of Enhancing DNA Damage Repair Frontiers in Cell and Developmental Biology · 2021 · 9 citations
    10. Planar Proton Minibeam Irradiation Elicits Spatially Confined DNA Damage in a Human Epidermis Model Cancers · 2022 · 8 citations
    11. Geranyl Acetate Attenuates Para-phenylenediamine-induced Cytotoxicity, DNA Damage, Apoptosis, and Inflammation in HaCaT Keratinocytes Iranian journal of pharmaceutical research · 2025 · 1 citations
    12. Association of DNA damage with vitamin D and hair heavy metals of obese women 2021 · 1 citations
    13. Prolonged use of finasteride-induced gonadal sex steroids alterations, DNA damage and menstrual bleeding in women Bioscience Reports · 2020 · 1 citations
    14. Araliadiol Protects Human Keratinocytes From Oxidative Stress, DNA Damage, and Apoptosis via Activation of Antioxidant Signaling Frontiers in Bioscience-Landmark · 2026
    15. 0950 Exploring hair aging through ex vivo induction of DNA damage and senescence Journal of Investigative Dermatology · 2025
    16. Flavonoids in safflower extract reduce cisplatin-induced damage to human follicle dermal papilla cells by inhibiting DNA damage and Rad17/Chk1/Cdc25C signaling Biocell · 2023
    17. Oxidative DNA damage level in relationship to zinc status in patients complaining hair fall, in Duhok city, Krg-Iraq: A case-control study International Journal of Health Sciences (IJHS) · 2022
    18. Nitrogen Mustard Induces DNA Damage and Structural Changes in Mouse Skin Hair Follicles The FASEB Journal · 2015
    19. DNA Damage, Checkpoint Responses, and Cell Cycle Control in Aging Stem Cells Else Kröner-Fresenius Symposia · 2012
    20. Booby Trap: Cancer gene spurs production of DNA-assaulting chemicals that alert and defuse rescue molecule (Cancer; Oxidative damage) Science of aging knowledge environment · 2002
    21. Irradiation-induced hair graying in mice: an experimental model to evaluate the effectiveness of interventions targeting oxidative stress, DNA damage prevention, and cellular senescence GeroScience · 2024
    22. Mdm2-p53 Signaling in Tissue Homeostasis and the DNA Damage Response: A Dissertation 2012
    23. Defects in mitochondrial DNA replication and oxidative damage in muscle of mtDNA mutator mice Free radical biology & medicine · 2014 · 53 citations
    24. Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model Frontiers in Immunology · 2020 · 48 citations
    25. Mitochondrial DNA Damage, Oxidative Stress, and Atherosclerosis Circulation · 2013 · 12 citations
    26. In Vivo Role of Vitamin D Receptor Signaling in UVB-Induced DNA Damage and Melanocyte Homeostasis 2016 · 10 citations
    27. 1360 Fate tracing of DNA-damaged hair follicle stem cells and their seno-differentiation clearance out of the niche 2023
    28. Finasteride-induced secondary infertility associated with sperm DNA damage Fertility and Sterility · 2011 · 36 citations
    29. Spironolactone, a Classic Potassium-Sparing Diuretic, Reduces Survivin Expression and Chemosensitizes Cancer Cells to Non-DNA-Damaging Anticancer Drugs Cancers · 2019 · 11 citations
    30. Scientific Opinion on the substantiation of health claims related to soy isoflavones and protection of DNA, proteins and lipids from oxidative damage (ID 1286, 4245), maintenance of normal blood LDL cholesterol concentrations (ID 1135, 1704a, 3093a), reduction of vasomotor symptoms associated with menopause (ID 1654, 1704b, 2140, 3093b, 3154, 3590), maintenance of normal skin tonicity (ID 1704a), contribution to normal hair growth (ID 1704a, 4254), “cardiovascular health” (ID 3587), treatment … EFSA journal · 2011 · 22 citations