Spironolactone Use Does Not Increase the Risk of Estrogen-Dependent Cancer Recurrence: A Retrospective Analysis

November 2020 in “ Journal of The American Academy of Dermatology ”

Shane Chapman, Adam Friedman, Patawut Bovonratwet, Alex Gu, Gaby Moawad

ascorbic acid vitamin C D-α-tocopherol vitamin E UVB-induced skin damage thymine dimers DNA damage UVB exposure sunburn reaction solar UV radiation UVB skin damage sunburn UV radiation

TLDR Taking vitamin C and vitamin E twice a day can help prevent sunburn and DNA damage from UVB exposure.

The study examined the impact of long-term oral intake of antioxidants ascorbic acid (vitamin C) and D-α-tocopherol (vitamin E) on UVB-induced skin damage in humans. Over a 3-month period, these vitamins significantly reduced the sunburn reaction to UVB exposure and decreased the amount of thymine dimers, a type of DNA damage, caused by UVB. The research concluded that taking ascorbic acid and D-α-tocopherol orally twice a day could serve as an effective and well-tolerated preventive treatment against the harmful effects of solar UV radiation.

View this study on jaad.org →

Discuss this study in the Community →

Related Community Posts Join

6 / 20 results

community Korean 2021 study shows efficacy of sulforaphane.

in Treatment 50 upvotes 2 years ago

Sulforaphane shows potential for hair regrowth, with users reporting reduced shedding and regrowth. Some users combine it with Minoxidil and finasteride for better results.

community I am actually regrowing my hairline without minoxidil or finasteride (mechanical stimulation)

128 upvotes 6 years ago

Regrowing hairline without the use of Minoxidil or Finasteride, and instead using mechanical stimulation such as Derma Roller, Nizoral, Zinc Pyrithione, Scalp Massage, Scalp Exercise, Fish Oil and other topical solutions. It is cautioned that there are risks associated with not using medically-prescribed treatments, but it is suggested to consider mechanical stimulation in addition to those prescribed treatments.

community 24M, thinning since 6 years. Starting my Journey gonna be using the big 4 ( 1mg Fin, 5% minoxidil, 1.5mm dermaroller, nizoral twice a week)

in Finasteride/Dutasteride 72 upvotes 2 years ago

A 24 year old who has been experiencing thinning hair for 6 years and is starting a course of treatment involving finasteride, minoxidil, dermarolling, and nizoral shampoo. Others are wishing them luck and offering advice on how to potentially recover from the condition.

community DIY treatment... Shedding completely stopped after 1.5 yrs

in Treatment 251 upvotes 3 years ago

Vitamin C mixed with shampoo stopped shedding and promoted hair regrowth after 1.5 years. Both the person and their wife experienced significant hair loss reduction with this method.

community Got a microscope camera. Here’s the difference between healthy and miniaturized hair

in Progress Pictures 492 upvotes 2 years ago

A user who shared progress pictures of their scalp using a microscope camera, demonstrating the difference between healthy and miniaturized hair. Various explanations for the cause of this were discussed, such as DHT build-up in scalp sebum causing an autoimmune response leading to inflammation and eventual hair loss, with some suggesting a do-it-yourself treatment involving adding ascorbic acid powder to shampoo.

community Thoughts on topical vitamin C (added to shampoo, or a serum) effecting hair growth, thickness etc?

in Product 1 year ago

The conversation discusses using topical vitamin C in shampoo or serum for hair growth and thickness. The user mentions using the Nioxin system to maintain thick hair and is curious about the effects of vitamin C on hair growth.

Similar Research

5 / 631 results

research The Potential Application of Nanocarriers in Delivering Topical Antioxidants

January 2025 in “Pharmaceuticals”

Nanocarriers can improve antioxidant delivery to the skin but face safety and production challenges.

research Nutritional Management of Menopausal Women

January 2017 in “Springer eBooks”

Eating a balanced diet with specific nutrients can help manage menopause symptoms and prevent related health issues.

research Oxidative Stress in Aging of Hair

126 citations, January 2009 in “International Journal of Trichology”

Oxidative stress contributes to hair graying and loss as we age.

research Potential Use of Spin Traps to Control ROS in Antipollution Cosmetics: A Review

4 citations, January 2018 in “Cosmetics”

Spin traps like PBN could protect skin from pollution and sunlight in cosmetics but need more research for safe use.

research Seaweeds as Source of Bioactive Substances and Skin Care Therapy: Cosmeceuticals, Algotherapy, and Thalassotherapy

182 citations, November 2018 in “Cosmetics”

Seaweeds have beneficial compounds for skin care, including anti-aging and protective effects.