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In this study, researchers differentiated human induced pluripotent stem cells into dermal papilla-like cells and observed gene expression dynamics during five stages of dermal differentiation, demonstrating the potential of these cells to interact with epidermal cells in functional assays.

In this study, topical quercetin was found to stimulate hair follicle growth and promote microvascular regrowth in mice, suggesting its potential for hair regrowth strategies.

This study investigated the molecular mechanisms of hair follicle morphogenesis in Ordos fine-wool sheep, identifying differential genes related to primary and secondary hair follicles, and providing important insights for improving wool quality and breeding strategies.

This study found that upper wound fibroblasts are crucial for hair follicle regeneration during wound healing and suggests that these cells, along with papillary fibroblasts, migrate within the wound.

This study utilized a pigmented human epidermal equivalent model to incorporate melanocytes into the epidermis and found enhanced differentiation potential compared to conventional in vitro systems, reflecting in vivo cellular trajectories and highlighting melanocyte-to-keratinocyte communication pathways.

This study used single-cell RNA sequencing to identify at least nine subpopulations of keratinocytes in human neonatal epidermis, revealing unexpected heterogeneity and complex differentiation trajectories.

This review highlights recent advances in CRISPR-based lineage tracing methods that can improve our understanding of skin stem cell behavior, regeneration, and disease, with potential applications in organoids and model organisms.

This study used single-cell RNA sequencing to map the cellular composition of sheep hair follicles, revealing differentiation pathways and potential molecular mechanisms for wool curvature, which may inform sheep breeding.

This study used cashmere goats to reveal distinct intermediate states of dermal papilla cells, each with specific roles in hair growth, shedding, and regeneration.

Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.

This study used single-cell RNA sequencing to create a detailed atlas of human scalp hair follicles and found that early-stage hair graying involves matrix hair progenitor depletion linked to P53 pathway activation.

This study found that dermal EZH2 plays a crucial role in controlling fibroblast differentiation by regulating Wnt/β-catenin and retinoic acid signaling during skin development.

The study found that dermal EZH2 plays a crucial role in coordinating dermal fibroblast differentiation and epidermal development by modulating Wnt/β-catenin and retinoic acid signaling.

This study found that the Polycomb Repressive Complex 2, particularly its component Ezh2, is crucial in regulating dermal fibroblast differentiation and epidermal keratinocyte proliferation during murine skin development.

This study observed that CIP/KIP proteins play a significant role in regulating cell cycle arrest and differentiation in human hair follicles, supporting hair growth and formation in the anagen phase.

This study found that overexpression of Hoxc13 in GC13 mouse models affects hair follicle differentiation by interacting with medulla-specific genes, particularly Foxq1, suggesting a regulatory pathway for medulla differentiation.

This study identified three symptom trajectory groups in individuals with PMDD, highlighting variations in symptom severity and duration across the luteal and follicular phases.

This chapter reviews genetic defects in female sexual differentiation, focusing on 46,XX disorders of sex development and the impact of genetic factors and sex steroids on development, but reports no new clinical findings.

This study found that genetic ablation of Tet genes in mice led to changes in hair structure and keratin gene expression, indicating a role for Tet-mediated 5hmC DNA oxidation in hair follicle development and cycling.

This review discusses the dynamic, niche-driven regulation of stem cell states in tissue homeostasis and regeneration, focusing on epithelial stem cells in the mammalian skin, intestine, and lung, without providing new experimental results.

This study found that dedifferentiated corneal epithelial cells can revert to a stem-cell-like state, aiding tissue homeostasis and repair, with this plasticity limited to the epithelial lineage and enhanced by niche-derived cytokines.

This research examined the transcriptional landscape of quiescent melanocyte stem cells (qMcSCs) in adult female mice, revealing significant heterogeneity within this cell population and identifying novel subpopulations that vary in immune privilege regulation, melanocyte differentiation potential, and neural crest potential.

This study found that ablating centrosomes in developing epidermis alters keratinocyte division without majorly affecting differentiation, suggesting early epidermal development is driven by high proliferation and cell delamination.

This study found that centrosome ablation in developing epidermis triggers cell surveillance pathways, resulting in thinner skin and halted hair follicle growth, while later stages of epidermal growth may operate independently of basal progenitor division orientation.

This study found that transcriptome profiling of cashmere goat skin revealed key genes and pathways involved in hair follicle initiation, differentiation, and maturation, which are critical for improving fleece production.

This study introduces Cell Journey, a new platform for visualizing RNA velocity in 3D, which aims to better capture complex cellular transitions in single-cell datasets compared to current 2D methods.

This study introduces a new method to isolate stem cells from the hair follicle outer root sheath of equine skin, demonstrating that these cells, named eMSCORS, proliferate efficiently and can differentiate similarly to adipose tissue-derived MSCs, offering a promising alternative for equine veterinary applications.

This study reported that rapamycin reduced murine cochlear organoid proliferation depending on concentration, but at a 10-nM dose, it significantly increased hair cell differentiation by enriching SOX2+ progenitors while suppressing cells lacking Sox2 at early proliferation stages.

This review discusses the diverse roles and characteristics of epidermal and dermal stem cells in skin regeneration and aging, highlighting their potential applications in regenerative medicine and reports no new clinical results.

This study reports on a patient whose symptoms, including trichoepitheliomas and clinical alopecia, may suggest a new syndrome possibly linked to myasthenia gravis.