Mature Adipocytes Inhibit the Antimicrobial Function of Dermal Adipogenic Stem Cells: An Explanation for Impaired Cutaneous Defense in Obesity

    April 2018 in “ Journal of Investigative Dermatology ”
    S.X. Chen, L. Zhang, Richard L. Gallo
    Studysummary This study found that in obese mice, local antimicrobial activity is reduced due to a loss of adipogenic stem cells and an increase in mature adipocytes, leading to higher susceptibility to skin infections.
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