Dermal incision with verteporfin Research/Science 11/21/2025
Dermal incision with verteporfin is being explored as a potential hair loss treatment by dermatologist Melissa Toyos, with promising before-and-after photos shared on social media. The conversation discusses its potential effectiveness compared to other treatments like Minoxidil, Finasteride, and RU58841.
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5 / 183 resultscommunity Result after 12 months oral finasteride & 8 months oral minoxidil. No side effects.
A 45-year-old male has been using oral finasteride for 12 months and oral minoxidil for 8 months to address hair loss, with plans for a hair transplant next year. He reports no side effects and some improvement, but acknowledges a transplant is needed for full restoration.
community (Serious) Updates and discussion, new treatments in development
Finasteride, minoxidil, and derma rolling are currently the best treatments for hair loss. New treatments like TDM-105795, GT20029, PP405, HMI 115, Tsuji, Scube 3, RU, JW0061, Topilutamide, and verteporfin show promise but have uncertain timelines.
community Another molecular pathway to promote scarless healing and regenerate hair follicles
Carnosic acid in rosemary extract may enhance skin repair and promote hair follicle regeneration. It could be used alone or with verteporfin for scarless healing after dermal wounding.
community Would Verteporfin be the true ‘cure’ as it could reverse a NW7 to a NW1?
Verteporfin might reverse severe hair loss but is still in early testing stages. It could be a future option for NW6-7, though expensive.
community Verteporfin and Microneedling
Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.
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6 / 39 results
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research Use of Verteporfin with Dermal Wounding to Regenerate New Hair in Androgenetic Alopecia
Verteporfin with dermal wounding may boost hair regrowth in thinning areas but not in bald spots.
research Use of Verteporfin to Regrow Hair and Reduce Fibrosis After Transplantation
Verteporfin may improve hair regrowth and reduce scarring after hair transplants.
research Dermal Fibrosis and the Current Scope of Hydrogel Strategies for Scarless Wound Healing
Hydrogels show promise for scarless wound healing by reducing skin fibrosis.
research Fibroblasts – The Cellular Choreographers of Wound Healing
Fibroblasts are key to wound healing by managing immune cells and forming scar tissue.
research Multimodal Molecular Analysis Reveals Divergent Trajectories of Wound Regeneration Versus Fibrosis
Verteporfin treatment in mice led to complete skin healing without scarring.