1 citations,
May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
65 citations,
July 2006 in “Journal of biological chemistry/The Journal of biological chemistry” The gene Foxq1, controlled by Hoxc13, is crucial for hair follicle differentiation.
3 citations,
June 2021 in “PLOS ONE” A topical BRAF inhibitor, vemurafenib, can speed up wound healing and promote hair growth, especially in diabetic patients.
32 citations,
May 2018 in “Cell Cycle” Melatonin helps Cashmere goats grow more hair by affecting certain genes and cell pathways.
December 2023 in “International journal of molecular sciences” Chromosomal differences affect how muscle cells respond to testosterone.
18 citations,
October 2017 in “PLOS ONE” The study concluded that similar pathways regulate hair growth in dogs and mice, and these pathways are disrupted in dogs with Alopecia X, affecting stem cells and hormone metabolism.
22 citations,
April 2020 in “Scientific reports” Changthangi goats have specific genes that help produce Pashmina wool.
23 citations,
July 2020 in “Aging Cell” Aging changes sugar molecules on skin stem cells, which may affect their ability to repair skin.
61 citations,
September 2010 in “Genomics” The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.
25 citations,
August 2017 in “Animal Biotechnology” Researchers found that certain RNA molecules might play a role in the growth of Cashmere goat hair.
36 citations,
January 2018 in “Scientific reports” Eating glucoraphanin can help prevent psychosis in offspring whose mothers had immune system activation.
August 2022 in “Precision Clinical Medicine” JAM-A helps hair regrowth in alopecia areata by protecting VCAN in skin cells.
January 2025 in “BMC Genomics” Long non-coding RNAs help regulate wool fineness in Gansu alpine fine-wool sheep.
April 2024 in “Human genomics” Identified genes linked to male-pattern baldness may help develop new treatments.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” AP-2α and AP-2β proteins are essential for healthy adult skin and hair.
32 citations,
April 2016 in “Journal of Investigative Dermatology” STAT5 activation is crucial for starting the hair growth phase.
December 2024 in “Animals” RORA may help regulate hair growth by affecting hair follicle stem cells.
550 citations,
December 2005 in “The Journal of clinical investigation/The journal of clinical investigation” Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Early regulatory T cells are crucial for normal skin pigmentation.
1 citations,
November 2023 in “BMC chemistry” Tadalafil and Finasteride may help treat aggressive melanoma.
6 citations,
December 2019 in “Frontiers in genetics” GLI1 might protect against the start of skin cancer and is not linked to cancer severity.
22 citations,
June 2012 in “PLOS ONE” Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.
March 2024 in “Research Square (Research Square)” Sex steroids affect the MafB gene differently in male and female hamsters.
19 citations,
September 2019 in “EMBO molecular medicine” Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.
January 2025 in “International Journal of Molecular Sciences” Non-liganded Vitamin D Receptor is crucial for healthy skin and hair.
69 citations,
December 2015 in “BMC plant biology” Three genes in Arabidopsis are important for plant growth and development by affecting sugar attachment to proteins.
YH0618 helps reduce chemotherapy-induced hair loss by targeting specific proteins and pathways.
November 2023 in “Cell Proliferation” A protein from fat-derived stem cells, DKK1, is linked to hair loss and blocking it may help treat alopecia areata.
1 citations,
September 2022 in “Pharmaceutics” The stiffness of a wound affects hair growth during healing, with less stiff areas growing more hair.
April 2017 in “Plastic and reconstructive surgery. Global open” Fetal scalp cells have more regenerative genes than adult cells, and decellularized muscle matrix is better for muscle repair than commercial alternatives.