25 citations
,
August 2010 in “Acta Biomaterialia” This study achieved a first by successfully forming large quantities of dermal papilla spheroidal microtissues, which retained their hair induction potential, using a micropatterned culture system.
In this review of autonomous robotic surgery, the authors explore the integration of AI and machine learning in surgical procedures, detailing both the advancements and challenges of these technologies, including ethical concerns and current regulatory frameworks.
July 2026 in “Acta Biomaterialia” This study introduced a bioengineering platform that creates early-stage hair peg-like structures within tissue-engineered skin substitutes by integrating human keratinocytes and dermal papilla cells with laser-micropatterned collagen scaffolds, providing a foundation for future appendage-inclusive skin regeneration efforts.
January 2005 in “Journal of Cutaneous Pathology” This report presents the first known case of a proliferating hybrid cyst containing both epidermoid and trichilemmal components on the scrotum of a 44-year-old man.
7 citations
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January 1990 in “Archives of Dermatological Research” Syringomas likely start in the upper dermis and form distinct luminal structures.
January 2014 in “Institutional Repositories DataBase (IRDB)” The study observed that cell spheres formed from mesenchymal cells of newborn mice skin exhibited upregulation of markers linked to hair follicle regeneration, suggesting a potential hibernation-like state for maintaining viability.
73 citations
,
February 2023 in “Polymers” This review discusses the unique properties, design, and fabrication of peptide hydrogels for biomedical applications, focusing on advances in drug delivery, gene therapy, and regenerative medicine; it reports no new clinical results.
2 citations
,
April 2022 in “PLoS ONE” This study reports that short exposure to vibration causes epithelial cells to retract filopodia, concentrate actin at their edges, and increase expression of the protease calpain, suggesting a mechanism for vibration-induced pain relief.
April 2026 in “Molecules” This study suggests that extracellular vesicles derived from Saccharomyces cerevisiae may enhance hair follicle-related cellular processes, highlighting their potential for biomedical and cosmetic applications.
9 citations
,
June 2011 in “American Journal of Dermatopathology” This report presents a case of molluscum contagiosum virus infection within an epidermoid cyst in a 13-year-old on long-term steroid treatment, highlighting its rare occurrence and need for histological examination for accurate diagnosis.
July 2025 in “Journal of Investigative Dermatology” Tissue-engineered skin substitutes can model junctional epidermolysis bullosa and may help develop gene therapy.
1 citations
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December 2024 in “ACS Biomaterials Science & Engineering” The patches could quickly deliver epilepsy treatment and reduce seizures.
1 citations
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February 2024 in “Journal of nanobiotechnology” This review explores how combining extracellular vesicles with hydrogels and utilizing 3D bioprinting technologies creates innovative composite systems for wound healing, offering advanced mechanical and biological support, while addressing challenges like degradation and regulatory issues in clinical applications.
December 2025 in “Advanced Healthcare Materials” This study introduces a spherical skin model that effectively mimics key features of human skin, offering a scalable and rapid alternative for non-animal dermatological and cosmetic testing.
6 citations
,
January 2015 in “Biochemical Society Transactions” This review discusses the role of Ysc84/SH3yl1 proteins in linking actin regulation to membrane morphology changes but reports no new experimental results.
December 2023 in “Journal of comparative pathology” This case report describes the first known instance of a dilated pore of Winer, a type of follicular cyst, identified in a dog, specifically a 9-year-old neutered Goldendoodle, which was surgically excised after causing pain due to periodic ruptures.
45 citations
,
December 2007 in “The FASEB journal” This study demonstrated that hair follicle bulge stem cells can form epidermis in a tissue-engineered skin model, highlighting the significance of K5/K17 filaments in slow-cycling stem cell subsets.
12 citations
,
February 2025 in “Scientific Reports” This study found that extracellular vesicles derived from mesenchymal stem cells and umbilical cord blood plasma enhanced wound healing and reduced scar formation in mice, suggesting their potential as therapeutic agents for skin repair.
2 citations
,
April 2012 in “American Journal of Dermatopathology” This report describes two cases of nevus lipomatosus superficialis with the unusual feature of dilated hair follicles, emphasizing the need for precise histopathological diagnosis to differentiate from similar conditions.
5 citations
,
April 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” In this review, researchers noted that liposomes, due to their ability to stabilize and target drugs, are effective carriers for treating various dermatological conditions such as acne and psoriasis when applied topically.
6 citations
,
January 2025 in “Journal of Materials Chemistry B” This review discusses liposome-composite hydrogel microspheres as drug delivery systems, detailing their fabrication techniques, properties, and applications, but it reports no new experimental results.
June 2020 in “Journal of Investigative Dermatology” This study found that human hair follicle dermal papilla cells and keratinocytes self-assembled differently in 3D spheroid co-cultures, providing insights into cell distribution and organogenesis during skin regeneration.
14 citations
,
February 2025 in “Pharmaceutics” This review highlights recent advancements in using niosomes as nanocarriers for improved delivery and sustained release of active cosmetic compounds, discussing their properties, applications, and future potential in cosmetic chemistry.
220 citations
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March 2020 in “Advanced functional materials” This review discusses the mechanisms and potential therapeutic benefits of mesenchymal stromal cell-derived extracellular vesicles delivered via biomaterials, but reports no new clinical results.
26 citations
,
March 2013 in “Journal of Biomedical Materials Research Part A” This study demonstrated that PEGDA hydrogel microwells successfully supported cell survival and proliferation while mimicking hair follicle architecture in vitro, suggesting a potential tool for hair follicle engineering.
7 citations
,
January 2023 in “Biofabrication” This study developed microfluidic-assisted GelMA-MSC/HAD-EPC microspheres that efficiently generated hair follicles in nude mice, suggesting a promising strategy for advancing hair-regenerative medicine.
9 citations
,
January 2018 in “Stem Cells International” The researchers reported that conditioned media from deer antler mesenchymal stem cells may enhance hair and skin regeneration by modulating cellular responses through secretory vesicles.
39 citations
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January 1998 in “Dermatology” The authors concluded that milia, steatocystoma multiplex, and eruptive vellus hair cysts may be subtypes of multiple pilosebaceous cysts with overlapping histologic features.
30 citations
,
December 2017 in “Advanced Healthcare Materials” This study reports that using nanogel and layer-by-layer self-assembly to encapsulate single dermal papilla cells can form cell spheroids that regenerate hair follicles successfully in a hair follicle regeneration model.
2 citations
,
October 2007 in “Kafrelsheikh Veterinary Medical Journal” This study examined the morphological features of buffalo lips, finding that their structure includes distinct layers of skin, muscle, connective tissue, and glands.