TLDR Liposomes are useful for treating skin conditions by effectively delivering drugs.
The document discussed the use of liposomes in dermatological diseases, highlighting their role as vesicles made of spherical phospholipids that are beneficial for topical drug applications. Liposomes were noted for their ability to carry both hydrophilic and lipophilic therapeutic agents due to their amphipathic nature, improving the stabilization of unstable drugs by encapsulating them. They were particularly advantageous for targeting drugs into pilosebaceous structures, making them useful in treating hair follicle-associated disorders. Liposomal encapsulated drugs were found effective in treating conditions such as acne, atopic dermatitis, psoriasis, vitiligo, superficial vein thrombosis, and hair removal.
3 citations
,
January 2022 in “Pharmaceutics” Nanostructured delivery systems could potentially improve hair loss treatment by targeting drugs to hair follicles, reducing side effects and dosage, but the best size, charge, and materials for these systems need further investigation.
130 citations
,
August 2020 in “Drug Design Development and Therapy” Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.
151 citations
,
July 2011 in “Archives of Dermatological Research” Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.
140 citations
,
January 2009 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Liposomes improve drug delivery and reduce skin irritation in dermatology.
10 citations
,
April 2016 in “Research and reports in transdermal drug delivery” Transfollicular drug delivery is promising but needs more research to improve and understand it better.