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In this study, extracellular vesicles from Saccharomyces cerevisiae demonstrated multifunctional bioactivity, enhancing cell proliferation and migration, reducing inflammation, and promoting collagen gene expression in hair follicle–related cells.

This review discusses the therapeutic potential of mesenchymal stem cell-derived small extracellular vesicles for chronic wound treatment and reports no new clinical results, emphasizing the need for further research on their large-scale production and engineering.

In this study, exosome-mimetic nanovesicles derived from ReNcell VM cells promoted hair growth in mice by enhancing dermal papilla cell proliferation and activating the Wnt/β-catenin signaling pathway.

This review discusses the potential role of extracellular vesicles in modulating hair follicle dynamics and reports no new clinical results; future investigations may inform treatment strategies for skin disorders.

This study designed a micromold template for creating controlled-sized, multicellular tumor spheroids, finding that HEK-293 cells formed consistent spheroids with high circularity and viability after 7 days, influenced by cell seeding density and treatment conditions.

In this study, researchers developed a biomacromolecular hydrogel to deliver plant-derived extracellular vesicles for treating androgenetic alopecia in a mouse model, which significantly improved hair regrowth and follicle density by activating Wnt/β-catenin signaling.

This review discusses using extracellular vesicles as less invasive surrogates for assessing drug-metabolizing enzymes and transporters, suggesting potential advancements in precision therapy, but reports no new clinical results.

In this study, intradermal injections of extracellular vesicles over six months were reported to be safe and effective in improving hair growth among patients with pattern hair loss, with favorable response linked to specific patient factors and treatment volumes.

This review discusses the potential of adipose-derived stem cell extracellular vesicles (ADSC-EVs) in skin regeneration, highlighting mechanisms like inflammation and angiogenesis, but reports no new clinical results; challenges and future prospects are also considered.

This paper reviews the state of knowledge on injectable cryogels, highlighting their unique properties such as shape-memory and mechanical integrity, which allow for minimally invasive delivery via needles and potential applications in oncology and regenerative medicine.

This study found that lymph vessel morphology and density in airways differed based on location and type of epithelium, with the highest density in the ciliated epithelium of the nasal passages and site-specific patterns apparent in both fetal and adult specimens.

This study found that human mesenchymal stem cell-derived extracellular vesicles promote the proliferation and migration of hair follicle cells and increase hair shaft elongation in cultured human hair follicles.

Collagen scaffolds in cell therapy can transform skin to be more resilient and pressure-responsive.

In this study, researchers developed a photocurable polyurethane resin for 3D printing, creating high-resolution elastomeric microwell arrays that effectively promote uniform spheroid formation and growth of A549 cells, which could aid in disease modeling and organoid research.

In this study, researchers developed a new method for producing dissolving microneedle array patches containing mesoporous silica nanoparticles, successfully confirming nanoparticle deposition and release in both ex vivo and in vivo models.

This review discusses the role of extracellular vesicles as therapeutic agents for wound healing and highlights the need for further research into their clinical applications.

This study demonstrated that gelatine-based hydrogel foams loaded with platelet extracellular vesicles (pEVs) promoted full wound closure in a chronic wound rat model within 14 days, suggesting potential for personalized treatment of chronic diabetic wounds.

In this study, iPSC-derived epidermal organoids demonstrated potential as a novel tool for regenerative medicine by producing high-performance extracellular vesicles that promote proliferation, migration, and angiogenesis in cell-free therapies for wound healing.

This review discusses the role of extracellular vesicles in psoriasis pathogenesis and their potential as therapeutic agents or drug delivery systems, but it reports no new clinical findings.

This study found that platelet-derived extracellular vesicles from apheresis platelets may effectively activate dermal papilla cells and promote hair follicle growth in a mouse model of hair regeneration.

This study's simulations revealed the complex "onion-like" organization of a lipid nanoemulsion droplet containing vitamins A and E for skin delivery, showing distinct concentration patterns of these vitamins within different layers of the nanodroplet.

This study found that mouse embryoid bodies adhered quickly and differentiated efficiently into cardiomyocytes on negatively charged poly(sodium p-styrene sulfonate) hydrogels, similar to their behavior on gelatin-coated polystyrene.

This study found that engineered extracellular vesicles (293F-EGF-EV), enriched in EGF mRNA, significantly aided skin wound healing in vitro and in a rat model by promoting fibroblast activity and improving wound recovery through processes like angiogenesis and reduced scarring.

This case report describes a 24-year-old male with eruptive vellus hair cysts on his forehead and explores the use of extraction videodermoscopy as a new, less invasive diagnostic method, potentially replacing the need for skin biopsy in diagnosing such skin conditions.

The researchers found that exosome-like vesicles from irradiated cheek skin in neonatal mice may offer protective effects against hair follicle loss after high-dose radiation exposure.

This review discusses how using hydrogels as a three-dimensional culture platform for mesenchymal stem cells might affect the production of extracellular vesicles, highlighting challenges in standardization and opportunities to boost EV yield via combined hydrogels and bioreactor methods.

This review discusses recent advances in using extracellular vesicles as a potential treatment for alopecia and highlights ongoing challenges in their clinical application and mass production; no new clinical results are reported.

This study found that medium/large extracellular vesicles derived from hair follicle and adipose tissue mesenchymal stromal cells both demonstrated significant neuroprotective and anti-inflammatory effects in cell cultures, highlighting their potential use as biopharmaceuticals for treating neurodegenerative diseases.

This review discusses the potential of extracellular vesicles from various sources as promising candidates for hair growth stimulation but notes that clinical trials are needed to confirm their effectiveness and safety.