TLDR Vesicles from irradiated mouse cheek skin help cells survive radiation.
The study investigated the protective effects of exosome-like vesicles (ELV) secreted from irradiated neonatal mouse cheek skin on hair follicle loss after high-dose radiation. Neonatal mice exposed to 7 Gy X-ray showed overall hair growth defects except on their cheeks, suggesting a protective substance was secreted. The researchers found that ELV from irradiated cheek skin increased cell survival in mouse fibroblast cell lines, indicating that these vesicles might help prevent hair follicle loss after radiation exposure.
37 citations,
June 2019 in “Stem cells” Special particles from skin cells can promote hair growth by activating a specific growth signal.
10 citations,
June 2003 in “PubMed” Radiation increases cell death in hair follicles, but certain treatments can protect against this effect.
1113 citations,
August 1999 in “The New England Journal of Medicine” Hair follicle biology advancements may lead to better hair growth disorder treatments.
38 citations,
June 2019 in “International Journal of Molecular Sciences” Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.
March 2024 in “Indian Journal of Dermatology/Indian journal of dermatology” Exosomes could be key in treating skin conditions and healing wounds.
15 citations,
January 2018 in “Biomedical Reports” Exosomes are important for skin health and could help diagnose and treat skin diseases.
2 citations,
January 2022 in “Stem cell biology and regenerative medicine” Extracellular vesicles, including exosomes from certain cells, can stimulate hair growth.
December 2024 in “Pharmaceutics” Extracellular vesicles show promise for treating psoriasis by reducing inflammation and skin lesions.
